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Current Green Chemistry

Author(s): Manoj Kumar Patel, Km Neha Shivhare*, Manish Kumar Jaiswal, Saurabh Kumar Tiwari, Ved Prakash, Rana Krishna Pal Singh and Ibadur Rahman Siddiqui

DOI: 10.2174/0122133461307610240903094350

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Electro-sustainable Synthesis: Rapid and Efficient Production of Benzothiazole Derivatives through Electrochemical Means for Sustainable Chemistry

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Abstract

Background: We generally focused on an environmentally green synthesis and we used to replace toxic methods, hazardous reaction conditions from the greener methods such as electro-organic synthesis, use of visible light as an energy source, natural and biodegradable green catalysts etc.

Objective: Synthesis of biologically-active benzothiazole derivatives via eco-compatible method is the objective of our research article.

Methods: Electrochemical method where electro-organic synthesis was carried out in an undivided cell at room temperature in the presence of lithium perchlorate as a supporting electrolyte and electricity was also utilized here instead of a chemical substance with a simple graphite-iron electrode combination.

Results: The generation of 2-substituted benzothiazoles was achieved through the amalgamation of bis(2- aminophenyl)disulfides with aromatic aldehydes under the influence of the electrodes. Products were obtained here with the satisfactory to excellent yields with the range of 64% - 91%.

Conclusion: In conclusion, for the synthesis of benzothiazole derivatives, a different aqueous phase, facile, simple and dexterous method that is free from any type of hazardous catalyst was reported. This protocol represents a novel synthetic concept and an eco-compatible pathway along with green chemistry expertise like usage of the nontoxic solvent with effortless work-up procedure.

Keywords: Electro-catalysed, benzothiazoles, green synthesis, eco-compatible, sustainable chemistry, electro-organic synthesis.

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