Recent Advances in Anti-Infective Drug Discovery

Author(s): Kanika Patel and Dinesh Kumar Patel*

DOI: 10.2174/0127724344297762240815073618

DownloadDownload PDF Flyer Cite As
Biological Potential of Oxoglaucine in Medicine for the Treatment of Human Disorders: An Update on Pharmacological Activities and Related Molecular Mechanism

Page: [77 - 91] Pages: 15

  • * (Excluding Mailing and Handling)

Abstract

Medicinal plants are an integral part of the medical system in many countries around the world. Natural products have been used as important biological sources for drug discovery over the past half-century. Alkaloids are a group of natural compounds that contain a basic nitrogen atom. Oxoglaucine is a phytochemical of the oxoaporphines class phytochemical isolated from Aquilegia ecalcarata Maxim, Corydalis yanhusuo, Chasmanthera dependens, and Xylopia aethiopica. The purpose of this study is to analyze all the scientific information about oxoglaucine in order to know the health-beneficial potential of oxoglaucine in medicine. The detailed pharmacological activities of oxoglaucine are analyzed and discussed in this review. The scientific data of the present review about oxoglaucine were collected from PubMed, Scopus, Science Direct, and Google using the terms oxoglaucine, oxoaporphines, alkaloid, phytochemical, pharmacological, and herbal medicine. The scientific findings of the present review article describe the biological importance and therapeutic effectiveness of oxoglaucine in medicine. The present article scientific data signified the biological potential of oxoglaucine against inflammatory diseases, arthritis, osteoarthritis, immune response, enterovirus, and poliovirus. Furthermore, its anticancer, antiaggregation, antifungal, antiprotozoal, and cytotoxic potential are also described in this review article. The scientific information in this article will be helpful to all the scientific peoples of biological science to understand the therapeutic potential of oxoglaucine in medicine.

Keywords: Oxoglaucine, inflammatory, arthritis, osteoarthritis, immune, enterovirus, anticancer, antiplatelet, antifungal, antiplasmodial, cytotoxic, medicine, oxoaporphines, alkaloid.