Abstract

Cesium carbonate is an alkali carbonate salt that has numerous applications and has been proven to be a mild inorganic base in organic synthesis. It has garnered significant attention due to its practicality in C-H functionalization and heteroatom-heteroatom bond formation reactions, in addition to its application in conventional synthetic transformations. In this six-year update, we have examined the most important applications of Cs₂CO₃ in organic synthesis from 2018 to the present, including the scope of the reaction and providing detailed explanations of the underlying mechanisms.

Keywords: Cesium carbonate (Cs₂CO₃), cesium salt, heterocycles, C-H functionalization, heteroatom-heteroatom bond formation, organic transformations, alcohols.