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Cardiovascular & Hematological Disorders-Drug Targets

Author(s): Sergey Yakushin, Arzu Gurbanova and Kristina Pereverzeva*

DOI: 10.2174/011871529X305833240708051508

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Kounis Syndrome: Review of Clinical Cases

Page: [83 - 97] Pages: 15

  • * (Excluding Mailing and Handling)

Abstract

Background: Kounis syndrome is defined as a combination of acute coronary syndrome and allergic reactions.

Objective: In this review, we aim to describe the etiological, clinical, and diagnostic characteristics of Kounis syndrome.

Methods: A literature search using PubMed was conducted for the past 32 years using keywords, resulting in the selection of 761 scientific papers. From these, 217 articles describing 235 clinical cases were selected. Patients under 18 years of age or without a confirmed diagnosis were excluded.

Results: Among the 235 patients, type I Kounis syndrome was observed in 49.7%, type II in 27.2%, type III in 5.9%, and a combination of types I and II in 1.0%; in 16.2%, it was not possible to classify the type of Kounis syndrome. The median age was 57 years, and 68.5% of the patients were male. The most common causes were antibiotics (32.3%) and non-steroidal anti-inflammatory drugs (24.3%). The clinical features included chest pain (59.1%), hypotension (74.2%), itching (30.6%), and dyspnea (30.6%). Electrocardiographic monitoring revealed ST-segment elevation in 42.9% and was normal in only 5.5% of patients. Coronary angiography was performed in 80.4% of the patients, revealing unchanged coronary arteries in 50.3% of cases.

Сonclusion: Allergic myocardial infarction is a serious complication of drug therapy.

[1]
Fassio, F.; Losappio, L.; Antolin-Amerigo, D.; Peveri, S.; Pala, G.; Preziosi, D.; Massaro, I.; Giuliani, G.; Gasperini, C.; Caminati, M.; Heffler, E. Kounis syndrome: A concise review with focus on management. Eur. J. Intern. Med., 2016, 30, 7-10.
[http://dx.doi.org/10.1016/j.ejim.2015.12.004] [PMID: 26795552]
[2]
Wong, S.W.; Ahmad Hatib, A. Kounis syndrome after administration of iopromide-based contrast. Zhonghua Minguo Xinzangxue Hui Zazhi, 2023, 39(4), 667-669.
[http://dx.doi.org/10.6515/ACS.202307_39(4).20230416B] [PMID: 37456935]
[3]
Zuluaga-Gómez, M.; González-Arroyave, D.; Ardila, C.M. Kounis syndrome secondary to laxative administration. Case Rep. Med., 2022, 2022, 1-5.
[http://dx.doi.org/10.1155/2022/6087176] [PMID: 35783461]
[4]
Gázquez, V.; Dalmau, G.; Gaig, P.; Gómez, C.; Navarro, S.; Mercé, J. Kounis syndrome: Report of 5 cases. J. Investig. Allergol. Clin. Immunol., 2010, 20(2), 162-165.
[PMID: 20461972]
[5]
Masuda, M.; Fujimoto, W.; Yamashita, S.; Takemoto, M.; Kuroda, K.; Imanishi, J.; Iwasaki, M.; Todoroki, T.; Okuda, M.; Hayashi, T. Recurrent cardiac arrests caused by Kounis syndrome without typical allergic symptoms. J. Cardiol. Cases, 2023, 27(2), 47-51.
[http://dx.doi.org/10.1016/j.jccase.2022.10.004] [PMID: 36788958]
[6]
Marchesini, D.; Esperide, A.; Tilli, P.; Santarelli, L.; Covino, M.; Carbone, L.; Franceschi, F. Allergic acute coronary syndrome: A case report with a concise review. Eur. Rev. Med. Pharmacol. Sci., 2020, 24(22), 11768-11772.
[http://dx.doi.org/10.26355/eurrev_202011_23830] [PMID: 33275246]
[7]
Vlahos, N.P.; Vavilis, G.K.; Giannelou, A.G.; Georgopoulou, C.N.; Kommata, V.J.; Kougias, C.T.; Tsartsalis, D.N.; Kounis, G.N.; Mazarakis, A.; Batsolaki, M.; Gouvelou-Deligianni, G.V.; Hahalis, G.; Kounis, N.G. Hypersensitivity to proton pump inhibitors: Lansoprazole-induced Kounis syndrome. Int. J. Cardiol., 2009, 134(3), e94-e96.
[http://dx.doi.org/10.1016/j.ijcard.2007.12.099] [PMID: 18378022]
[8]
Calogiuri, G.F.; Nettis, E.; Di Leo, E.; Vacca, A.; Ferrannini, A.; Kounis, N.G. Kounis syndrome induced by intravenous administration of piperacillin/tazobactam: A case report. Int. J. Cardiol., 2012, 155(3), e42-e44.
[http://dx.doi.org/10.1016/j.ijcard.2011.07.049] [PMID: 21839530]
[9]
Tosoni, C.; Cinquini, M.; Gretter, V.; Minetti, S.; Rizzini, F.L. Beware of the dog. J. Cardiovasc. Med., 2011, 12(9), 686-688.
[http://dx.doi.org/10.2459/JCM.0b013e32833dadd5] [PMID: 20671566]
[10]
Alves, M.F.; Pitta, M.L.; Peres, M.; Leal, M.; Almeida, A.G.; Ferreira da Silva, G. Cardiac Apical Aneurysm secondary to ibuprofen-induced type 1-Kounis syndrome. Int. J. Cardiol., 2012, 158(2), e41-e43.
[http://dx.doi.org/10.1016/j.ijcard.2011.10.026] [PMID: 22104989]
[11]
Lombardi, N.; Pugi, A.; Maggini, V.; Lenti, M.C.; Mugelli, A.; Cecchi, E.; Vannacci, A. Underdiagnosis and pharmacovigilance. The case of allergic acute coronary syndrome (Kounis syndrome). Int. J. Cardiol., 2013, 168(5), 5054-5055.
[http://dx.doi.org/10.1016/j.ijcard.2013.07.209] [PMID: 23954011]
[12]
Saleh, A.A. Kounis syndrome: acute inferior myocardial infarction with atroventricular node block due to ceftriaxone: a first reported case. Ann. Saudi Med., 2014, 34(3), 250-253.
[http://dx.doi.org/10.5144/0256-4947.2014.250] [PMID: 25266187]
[13]
Barbarroja-Escudero, J.; Sánchez-González, M.J.; Antolín-Amérigo, D.; Rodríguez-Rodríguez, M.; Salinas, P.; Fernández-Ortiz, A.; Alvarez-Mon, M. Kounis syndrome induced by cefditoren pivoxil. Int. J. Cardiol., 2016, 207, 112-114.
[http://dx.doi.org/10.1016/j.ijcard.2016.01.103] [PMID: 26800128]
[14]
Mendez Diaz, Y.; Gómez Torrijos, E.; Moreno Lozano, L.; Extremera Ortega, A.M.; García Rodríguez, R.; Hornos López, M.C.; Pineda de la Rosa, F.; Borja Segade, J. Immunoglobulin E–mediated severe allergy to hyoscine butylbromide. J. Investig. Allergol. Clin. Immunol., 2018, 28(4), 255-254.
[http://dx.doi.org/10.18176/jiaci.0247] [PMID: 30073956]
[15]
Mori, E.; Ikeda, H.; Ueno, T.; Kai, H.; Haramaki, N.; Hashing, T.; Ichiki, K.; Katoh, A.; Eguchi, H.; Ueyama, T.; Imaizumi, T. Vasospastic angina induced by nonsteroidal anti-inflammatory drugs. Clin. Cardiol., 1997, 20(7), 656-658.
[http://dx.doi.org/10.1002/clc.4960200713] [PMID: 9220183]
[16]
Blanco, V.M.; Möller, I.; Catalán, F.; Casares, G. Acute myocardial infarction during a diclofenac-associated anaphylactic reaction. Med. Clín., 2003, 121(7), 278.
[http://dx.doi.org/10.1016/S0025-7753(03)75196-3] [PMID: 12975044]
[17]
Cakar, M.A.; Gündüz, H.; Kocayiğit, I.; Binak, D.F.; Vatan, M.B.; Tamer, A. Acute coronary syndrome due to diclofenac potassium induced anaphylaxis: Two Kounis syndrome variants in the same patient. Anadolu Kardiyol. Derg., 2011, 11(1), 88-89.
[http://dx.doi.org/10.5152/akd.2011.017] [PMID: 21220239]
[18]
Rodrigues, M.C.L.; Coelho, D.; Granja, C. Drugs that may provoke Kounis syndrome. Braz. J. Anesthesiol., 2013, 63(5), 426-428.
[http://dx.doi.org/10.1016/j.bjan.2013.04.006] [PMID: 24263049]
[19]
Tiwari, A.; Tomar, G.; Ganguly, S.; Kapoor, M. Kounis syndrome resulting from anaphylaxis to diclofenac. Indian J. Anaesth., 2013, 57(3), 282-284.
[http://dx.doi.org/10.4103/0019-5049.115614] [PMID: 23983288]
[20]
Sahinkus, S.; Yilmaz, S.; Yaylaci, S.; Can, Y.; Kocayigit, I.; Gündüz, H. Kounis syndrome due to diclofenac injection. Alban Med J., 2016, 1, 63-66.
[21]
Gunes, H.; Turan Sonmez, F.; Saritas, A.; Koksal, Y. Kounis syndrome Induced by oral intake of diclofenac potassium. Iran. J. Allergy Asthma Immunol., 2017, 16(6), 565-568.
[PMID: 29338163]
[22]
Yildirim, T.; Yi̇ldi̇ri̇m, S.E. A forgotten cause of myocardial infarction in an octogenarian patient: Type 1 Kounis syndrome. Balıkesir Med. J., 2019, 3(3), 165-167.
[http://dx.doi.org/10.33716/bmedj.599198]
[23]
Özdemir, E.; Karakaya, Z.; Karaca, M.; Topal, F.; Payza, U. Recurrent diclofenac-induced acute myocardial infarction: An interesting case with wandering ST-segment elevation. Hong Kong J. Emerg. Med., 2020, 27(5), 304-307.
[http://dx.doi.org/10.1177/1024907919845526]
[24]
Rui, T.; Sani, H.; Syazana, N. A case of acute st-elevation myocardial infarction (STEMI) secondary to anaphylactic reaction: Type 2 Kounis syndrome. Malay.J. Med. Heal. Sci., 2021, 17, 314-136.
[25]
Garcia-Nunez, I.; Algaba-Marmol, M.A.; Ignacio-Garcia, J.M. Kounis syndrome after lidocaine use. J. Investig. Allergol. Clin. Immunol., 2023, 33(4), 312-313.
[http://dx.doi.org/10.18176/jiaci.0876] [PMID: 36515651]
[26]
La Cognata, O.; Trimarchi, G.; Lo Savio, A.; Virga, V.; Andò, G.; de Gregorio, C. Kounis syndrome in a patient with multivessel coronary artery disease and DRESS. Clin. Case Rep., 2023, 11(3), e7121.
[http://dx.doi.org/10.1002/ccr3.7121] [PMID: 36950673]
[27]
Alarcón Gallardo, E.; Escudero Apesteguía, R.; Sanz Bescós, C. ATAK complex due to amoxicillin. A case report. J. Investig. Allergol. Clin. Immunol., 2023, 34(1), 62-64.
[http://dx.doi.org/10.18176/jiaci.0921] [PMID: 37294099]
[28]
Yılmaz, M.; Korkmaz, H. Kounis syndrome: a paradoxal non-ST elevation myocardial infarction case after triamcinolone treatment for dermatitis. Turk Kardiyol. Dern. Ars., 2017, 46(3), 223-227.
[http://dx.doi.org/10.5543/tkda.2017.58827] [PMID: 29664430]
[29]
Canpolat, U.; Şahiner, L.; Aytemir, K.; Oto, A. Allergic reaction to proton pump ınhibitor: Pantoprazole ınduced Kounis syndrome. Int. J. Cardiol., 2012, 159(2), e27-e28.
[http://dx.doi.org/10.1016/j.ijcard.2011.11.059] [PMID: 22192298]
[30]
Tambe, V.; Tambe, A.; Goodman, A.; Shepherd, Z. Carboplatin-Induced Kounis syndrome. Am. J. Ther., 2020, 27(6), e647-e652.
[http://dx.doi.org/10.1097/MJT.0000000000001027] [PMID: 31567140]
[31]
Navarro-Navajas, A.; Casallas, I.; Isaza, D.; Ortiz, P.; Baracaldo-Santamaría, D.; Calderon-Ospina, C.A. Type III Kounis syndrome secondary to ciprofloxacin-induced hypersensitivity. Medicina, 2022, 58(7), 855.
[http://dx.doi.org/10.3390/medicina58070855] [PMID: 35888574]
[32]
Ramos Jovani, M.; Vázquez, S.; Regueiro Cueva, A.; Farrero, M. Metamizol-induced vasospasm: Kounis syndrome : An often overlooked diagnosis. Emergencias, 2022, 34(2), 155-156.
[PMID: 35275472]
[33]
Sidahmed, S.; Shafi, S.; Bala, A.; Zaitoun, A.; Bachuwa, G. Kounis syndrome: Allergic Vasospastic Cardiac Event. Cureus, 2020, 12(9), e10498.
[http://dx.doi.org/10.7759/cureus.10498] [PMID: 33094042]
[34]
Moloney, N.; Paget, S.; Keijzers, G. Kounis syndrome: Anaphylaxis causing coronary occlusion. Emerg. Med. Australas., 2019, 31(5), 903-905.
[http://dx.doi.org/10.1111/1742-6723.13377] [PMID: 31419012]
[35]
Leibee, C.; Getachew, B.; Ehmann, M.R. Vancomycin-induced Kounis syndrome. Am. J. Emerg. Med., 2019, 37(9), 1806.e3-1806.e5.
[http://dx.doi.org/10.1016/j.ajem.2019.06.004] [PMID: 31182359]
[36]
Yesin, M.; Kalçık, M.; Gürsoy, M.O.; Karakoyun, S.; Çağdaş, M.; Özkan, M. Acute myocardial infarction in a patient suffering from penicillin-induced laryngeal edema. Wien. Klin. Wochenschr., 2017, 129(13-14), 509-511.
[http://dx.doi.org/10.1007/s00508-017-1183-1] [PMID: 28255796]
[37]
Catarina Lameiras; Ana Corte-Real; Ana Órfão; Lopes, M.M.; Dória, M.D.C. Metamizole-Induced Type I Kounis syndrome. Eur. J. Case Rep. Intern. Med., 2021, 8(3), 002249.
[http://dx.doi.org/10.12890/2021_002249] [PMID: 33768068]
[38]
Fox, D.J.; Gray, T.P.; Fath-Ordoubadi, F. Myocardial infarction after aspirin treatment. J. R. Soc. Med., 2005, 98(1), 21-23.
[http://dx.doi.org/10.1177/014107680509800108] [PMID: 15632231]
[39]
Tavil, Y.; Turfan, M.; Türkoğlu, S.; Abacı, A. Kounis syndrome secondary to amoxicillin/clavulanic acid use. Int. J. Cardiol., 2008, 124(1), e4-e7.
[http://dx.doi.org/10.1016/j.ijcard.2006.11.165] [PMID: 17360053]
[40]
Vivas, D.; Rubira, J.C.G.; Ortiz, A.F.; Macaya, C. Coronary spasm and hypersensitivity to amoxicillin: Kounis or not Kounis syndrome? Int. J. Cardiol., 2008, 128(2), 279-281.
[http://dx.doi.org/10.1016/j.ijcard.2007.06.029] [PMID: 17707099]
[41]
Biteker, M.; Duran, N.E.; Biteker, F.S.; Gündüz, S.; Gökdeniz, T.; Kaya, H.; Astarcıoğlu, M.A.; Özkan, M. Kounis syndrome secondary to cefuroxime-axetil use in an octogenarian. J. Am. Geriatr. Soc., 2008, 56(9), 1757-1758.
[http://dx.doi.org/10.1111/j.1532-5415.2008.01912.x] [PMID: 19166448]
[42]
Almpanis, G.; Siahos, S.; Karogiannis, N.C.; Mazarakis, A.; Niarchos, C.; Kounis, G.N.; Kounis, N.G. Kounis syndrome: Two extraordinary cases. Int. J. Cardiol., 2011, 147(2), e35-e38.
[http://dx.doi.org/10.1016/j.ijcard.2009.01.031] [PMID: 19203807]
[43]
Kumar, A.; Berko, N.S.; Gothwal, R.; Tamarin, F.; Jesmajian, S.S. Kounis syndrome secondary to ibuprofen use. Int. J. Cardiol., 2009, 137(3), e79-e80.
[http://dx.doi.org/10.1016/j.ijcard.2009.04.049] [PMID: 19482364]
[44]
Akyel, A.; Alsancak, Y.; Yayla, Ç.; Şahinarslan, A.; Özdemir, M. Acute inferior myocardial infarction with low atrial rhythm due to propyphenazone: Kounis syndrome. Int. J. Cardiol., 2011, 148(3), 352-353.
[http://dx.doi.org/10.1016/j.ijcard.2010.05.038] [PMID: 20541820]
[45]
Murat, S.N.; Karasu, B.B.; Ornek, E.; Akdemir, R. Cefuroxime-axetil induced allergic angina: An insight into classification management of Kounis syndrome. Int. J. Cardiol., 2011, 151(2), e53-e55.
[http://dx.doi.org/10.1016/j.ijcard.2010.04.086] [PMID: 20605239]
[46]
Almpanis, G.; Mazarakis, A.; Tsigkas, G.; Koutsojannis, C.; Kounis, G.N.; Kounis, N.G. Acute stent thrombosis and atopy: Implications for Kounis syndrome. Int. J. Cardiol., 2010, 145(2), 398-400.
[http://dx.doi.org/10.1016/j.ijcard.2010.04.028] [PMID: 20537420]
[47]
Viana-Tejedor, A.; Espinosa, M.Á.; Cuesta, J.; Núñez, A.; Bueno, H.; Fernández-Avilés, F. Kounis syndrome secondary to amoxicillin use in an asthmatic patient. Int. J. Cardiol., 2011, 150(3), e113-e115.
[http://dx.doi.org/10.1016/j.ijcard.2010.02.066] [PMID: 20223532]
[48]
İlhan, E.; Güvenç, T.S.; Poyraz, E.; Ayhan, E.; Soylu, Ö. Kounis syndrome secondary to cefuroxime axetil use in an asthmatic patient. Int. J. Cardiol., 2009, 137(3), e67-e69.
[http://dx.doi.org/10.1016/j.ijcard.2009.04.026] [PMID: 19428133]
[49]
Oneglia, C.; Kounis, N.G.; Beretta, G.; Ghizzoni, G.; Gualeni, A.; Berti, M. Kounis syndrome in a patient with ovarian cancer and allergy to iodinated contrast media: Report of a case. Int. J. Cardiol., 2011, 149(2), e62-e65.
[http://dx.doi.org/10.1016/j.ijcard.2009.03.104] [PMID: 19395094]
[50]
Stelts, S.; Taylor, M.H.; Nappi, J.; Van Bakel, A.B. Mesalamine-associated hypersensitivity myocarditis in ulcerative colitis. Ann. Pharmacother., 2008, 42(6), 904-905.
[http://dx.doi.org/10.1345/aph.1K288] [PMID: 18430794]
[51]
Izgi, C.; Cevik, C.; Nugent, K. Severe myocardial ischemia after concentrated epinephrine use for the treatment of anaphylaxis: Kounis syndrome or epinephrine effect? Heart Lung, 2010, 39(2), 160-163.
[http://dx.doi.org/10.1016/j.hrtlng.2009.06.012] [PMID: 20207277]
[52]
Baroni, M.; Todd, S.; Pattarino, F.; Doni, F. Carboplatin-induced Kounis syndrome. J. Cardiol. Cases, 2011, 4(1), e58-e61.
[http://dx.doi.org/10.1016/j.jccase.2011.04.004] [PMID: 30532871]
[53]
Mazarakis, A.; Almpanis, G.C.; Papathanasiou, P.; Kounis, N.G. Kounis syndrome uncovers critical left main coronary disease: The question of administering epinephrine. Int. J. Cardiol., 2012, 157(3), e43-e45.
[http://dx.doi.org/10.1016/j.ijcard.2011.09.075] [PMID: 21996416]
[54]
Caglar, F.N.T.; Caglar, I.M.; Coskun, U.; Ugurlucan, M.; Okcun, B. Kounis syndrome: myocardial infarction secondary to an allergic insult a rare clinical entity. Acta Cardiol., 2011, 66(4), 559-562.
[http://dx.doi.org/10.1080/AC.66.4.2126625] [PMID: 21894822]
[55]
Kounis, N.G.; Tsigkas, G.G.; Almpanis, G.; Mazarakis, A. Kounis syndrome is likely culprit of coronary vasospasm induced by capecitabine. J. Oncol. Pharm. Pract., 2012, 18(2), 316-318.
[http://dx.doi.org/10.1177/1078155211423118] [PMID: 22020660]
[56]
Schwartz, B.G.; Daulat, S.; Kuiper, J. The Kounis-Zavras syndrome with the Samter-Beer triad. Proc. Bayl. Univ. Med. Cent., 2011, 24(2), 107-109.
[http://dx.doi.org/10.1080/08998280.2011.11928695] [PMID: 21566756]
[57]
Venturini, E.; Magni, L.; Kounis, N.G. Amoxicillin-induced Kounis syndrome manifesting as late stent thrombosis. Int. J. Cardiol., 2011, 151(1), e26-e28.
[http://dx.doi.org/10.1016/j.ijcard.2010.04.069] [PMID: 20471121]
[58]
Almpanis, G.C.; Mazarakis, A.; Dimopoulos, D.A.; Tragotsalou, N.A.; Kounis, G.N.; Kounis, N.G.; Alexopoulos, D. The conundrum of hypersensitivity cardiac disease: Hypersensitivity myocarditis, acute hypersensitivity coronary syndrome (Kounis syndrome) or both? Int. J. Cardiol., 2011, 148(2), 237-240.
[http://dx.doi.org/10.1016/j.ijcard.2009.09.534] [PMID: 19892418]
[59]
Tsigkas, G.; Chouchoulis, K.; Theodoropoulos, K.; Kounis, N.G.; Alexopoulos, D. Allergic reaction reveals a non-lethal late stent thrombosis. A new subtype of Kounis syndrome? Int. J. Cardiol., 2011, 149(2), 281-282.
[http://dx.doi.org/10.1016/j.ijcard.2011.02.060] [PMID: 21429602]
[60]
Gori, T.; Münzel, T. A case of coronary hypersensitivity (Kounis) syndrome associated with mid-ventricular ballooning pattern, intracoronary thrombosis and troponin elevation. Int. J. Cardiol., 2011, 149(3), 377-378.
[http://dx.doi.org/10.1016/j.ijcard.2011.02.066] [PMID: 21420182]
[61]
Chang, P.H.; Hung, M.J.; Yeh, K.Y.; Yang, S.Y.; Wang, C.H. Oxaliplatin-induced coronary vasospasm manifesting as Kounis syndrome: A case report. J. Clin. Oncol., 2011, 29(31), e776-e778.
[http://dx.doi.org/10.1200/JCO.2011.36.4265] [PMID: 21969496]
[62]
Karabay, C.Y.; Gecmen, C.; Aung, S.M.; Guler, A.; Candan, O.; Batgerel, U.; Kalayci, A.; Kirma, C. Is 5-fluorouracil-induced vasospasm a Kounis syndrome? A diagnostic challenge. Perfusion, 2011, 26(6), 542-545.
[http://dx.doi.org/10.1177/0267659111410347] [PMID: 21628340]
[63]
Adatia, S.; Sanghani, S.; Sanzgiri, P.; Chauhan, V.; Hastak, S. Acute myocardial infarction following intravenous tissue plasminogen activator for acute ischemic stroke: An unknown danger. Ann. Indian Acad. Neurol., 2010, 13(1), 64-66.
[http://dx.doi.org/10.4103/0972-2327.61282] [PMID: 20436751]
[64]
Campo, G.; Pavasini, R.; Pollina, A.; Petrini, L.; Ferrari, R. Kounis–Zavras syndrome presenting with ventricular arrhythmias and cardiogenic shock. J. Cardiol. Cases, 2013, 7(3), e74-e77.
[http://dx.doi.org/10.1016/j.jccase.2012.11.003] [PMID: 30533127]
[65]
Tok, D.; Ozcan, F.; Sentürk, B.; Gölbaşı, Z. A case of acute coronary syndrome following the use of parenteral penicillin: Kounis syndrome. Turk Kardiyol. Dern. Ars., 2012, 40(7), 615-619.
[http://dx.doi.org/10.5543/tkda.2012.54077] [PMID: 23363946]
[66]
Akyel, A.; Murat, S.N.; Çay, S.; Kurtul, A.; Öcek, A.H.; Cankurt, T. Late drug eluting stent thrombosis due to acemetacine: Type III Kounis syndrome. Int. J. Cardiol., 2012, 155(3), 461-462.
[http://dx.doi.org/10.1016/j.ijcard.2011.12.032] [PMID: 22222426]
[67]
Mazarakis, A.; Karogiannis, N.C.; Almpanis, G.C.; Servos, G.; Dimopoulos, D.A.; Tsigkas, G.; Kounis, N.G. Subclinical and clinical presentation of Kounis syndrome: Another cause of troponin elevation? Int. J. Cardiol., 2012, 157(2), 258-260.
[http://dx.doi.org/10.1016/j.ijcard.2012.03.110] [PMID: 22483259]
[68]
Aykan, A.C.; Zehir, R.; Karabay, C.Y.; Özkan, M. A case of Kounis syndrome presented with sudden cardiac death. Anadolu Kardiyol. Derg., 2012, 12(7), 599-600.
[http://dx.doi.org/10.5152/akd.2012.191] [PMID: 22877900]
[69]
Garcipérez de Vargas, F.J.; Mendoza, J.; Sánchez-Calderón, P.; Ortiz, C.; Porro, R.; Mogollón-Jiménez, M.V. Cardiogenic shock secondary to metamizole-induced type II Kounis syndrome. Rev. Esp. Cardiol., 2012, 65(12), 1138-1139.
[http://dx.doi.org/10.1016/j.rec.2012.04.011] [PMID: 22818816]
[70]
Akoz, A.; Bayramoglu, A.; Uzkeser, M.; Kantarci, M.; Aksakal, E.; Emet, M. Two questions for Kounis syndrome: can we use magnetic resonance imaging in the diagnosis and does ST elevation correlates with troponin levels? Am. J. Emerg. Med., 2012, 30(9), 2086.e5-2086.e7.
[http://dx.doi.org/10.1016/j.ajem.2011.12.016] [PMID: 22386343]
[71]
Yurtdaš, M.; Aydin, M.K. A case of coronary spasm with resultant acute myocardial infarction: Likely the result of an allergic reaction. Intern. Med., 2012, 51(16), 2161-2164.
[http://dx.doi.org/10.2169/internalmedicine.51.7852] [PMID: 22892496]
[72]
Tekin, Y.K.; Tekin, G. Acute inferior myocardial infarction after injection of etofenamate. Turk Kardiyol. Dern. Ars., 2012, 40(8), 733-735.
[http://dx.doi.org/10.5543/tkda.2012.03592] [PMID: 23518891]
[73]
Itani, O.; Jazzar, M.; Hammoud, R.; Azar, M.; Shaaban, J. Allergic myocardial ischemia causing reversible hemodynamic collapse during gastroscopy. Anesth. Essays Res., 2012, 6(1), 98-100.
[http://dx.doi.org/10.4103/0259-1162.103388] [PMID: 25885514]
[74]
Maragkoudakis, S.; Hamilos, M.; Kallergis, E.; Vardas, P. Type 2 Kounis syndrome in an allergic woman: An uncommon presentation of acute coronary syndrome. J. Cardiol. Cases, 2013, 8(6), 176-178.
[http://dx.doi.org/10.1016/j.jccase.2013.08.003] [PMID: 30534285]
[75]
Dazy, K.; Walters, D.; Holland, C.; Baldwin, J. Anaphylaxis mediated myocardial infarction in a coronary graft: A new variant of Kounis syndrome (a case report). Int. J. Cardiol., 2013, 168(2), e84-e85.
[http://dx.doi.org/10.1016/j.ijcard.2013.07.044] [PMID: 23928337]
[76]
Acikel, S.; Ertem, A.G.; Arslantas, U.; Cimen, T.; Dogan, M.; Yeter, E. From treatment to diagnosis of Kounis syndrome in the catherization laboratory: The resolution of vasospastic angina after intracoronary tirofiban and nitrate therapy. Int. J. Cardiol., 2013, 168(3), 2943-2946.
[http://dx.doi.org/10.1016/j.ijcard.2013.03.172] [PMID: 23642606]
[77]
Oshima, T.; Ikutomi, M.; Ishiwata, J.; Ouchi, K.; Kato, M.; Amaki, T.; Nakamura, F. Kounis syndrome caused by aspirin-induced asthma. Int. J. Cardiol., 2014, 175(3), e37-e39.
[http://dx.doi.org/10.1016/j.ijcard.2014.05.008] [PMID: 24857324]
[78]
Çeliker, M.; Tuncer, M.; Şekeralmaz, A. A case with repeated recurrent acute coronary syndrome due to Pseudoephedrine use: Kounis syndrome. Case Rep. Med., 2014, 2014, 1-4.
[http://dx.doi.org/10.1155/2014/742905] [PMID: 25435880]
[79]
Esber, C.; Breathett, K.; Sachak, T.; Moore, S.; Lilly, S.M. Acute myocardial infarction in patient with triple negative breast cancer after paclitaxel infusion: A case report. Cardiol. Res., 2014, 5(3-4), 108-111.
[http://dx.doi.org/10.14740/cr325w] [PMID: 28348706]
[80]
Bilginoglu, M.; Akyel, A.; Doğan, M.; Sunman, H.; Yeter, E. Acute coronary syndrome secondary to clarithromycin: The first case and review of the literature. Turk Kardiyol. Dern. Ars., 2014, 42(5), 461-463.
[http://dx.doi.org/10.5543/tkda.2014.92891] [PMID: 25080953]
[81]
Venkateswararao, S.; Rajendiran, G.; Sundaram, R.S.; Mounika, G. Kounis syndrome secondary to intravenous cephalosporin administration. J. Pharmacol. Pharmacother., 2015, 6(4), 225-227.
[http://dx.doi.org/10.4103/0976-500X.171877] [PMID: 26813799]
[82]
Josefsson, J.; Fröbert, O. Losartan-induced coronary artery spasm. BMJ Case Rep., 2012, 2012, bcr2012006252.
[http://dx.doi.org/10.1136/bcr-2012-006252] [PMID: 23093500]
[83]
Ralapanawa, D.M.P.; Kularatne, S.A.M. Kounis syndrome secondary to amoxicillin/clavulanic acid administration: A case report and review of literature. BMC Res. Notes, 2015, 8(1), 97.
[http://dx.doi.org/10.1186/s13104-015-1072-5] [PMID: 25889048]
[84]
Ntuli, P.M.; Makambwa, E. Kounis syndrome. S. Afr. Med. J., 2015, 105(10), 878.
[http://dx.doi.org/10.7196/SAMJnew.8767] [PMID: 26636160]
[85]
Ateş, A.H.; Kul, S. Acute coronary syndrome due to midazolam use: Kounis syndrome during a transurethral prostatectomy. Turk: Kardiyol. Dern. Ars., 2015, 43(6), 558-561.
[http://dx.doi.org/10.5543/tkda.2015.44567] [PMID: 26363750]
[86]
Baillie, T.J.; Scherer, D.J.; Wong, D.T.L.; Steele, P.M. Kounis syndrome and hypersensitivity myocarditis : One and the same? Insights from cardiac magnetic resonance imaging. J. Cardiol. Cases, 2015, 12(4), 119-122.
[http://dx.doi.org/10.1016/j.jccase.2015.05.012] [PMID: 30546573]
[87]
Ihdayhid, A.R.; Rankin, J. Kounis syndrome with Samter–Beer triad treated with intracoronary adrenaline. Catheter. Cardiovasc. Interv., 2015, 86(6), E263-E267.
[http://dx.doi.org/10.1002/ccd.25960] [PMID: 26257014]
[88]
Buturak, A.; Norgaz, T.; Gorgulu, S. Brivudine induced coronary vasospasm as a manifestation of Kounis syndrome: First report. Int. J. Cardiol., 2015, 185, 4-6.
[http://dx.doi.org/10.1016/j.ijcard.2015.03.082] [PMID: 25777280]
[89]
Gormel, S.; Ege, T.; Koklu, M.; Celik, M.; Yuksel, U.C. Acute lateral myocardial infarction secondary to tramadol-induced Kounis syndrome. J. Cardiothorac. Vasc. Anesth., 2015, 29(6), 1599-1602.
[http://dx.doi.org/10.1053/j.jvca.2015.02.001] [PMID: 25939964]
[90]
Nishi, M.; Zen, K.; Kambayashi, D.; Asada, S.; Yamaguchi, S.; Tatsukawa, H. Stent dislodgement induced by a vasodilator used for severe coronary artery spasm caused by Kounis syndrome. Cardiovasc. Interv. Ther., 2016, 31(1), 61-64.
[http://dx.doi.org/10.1007/s12928-015-0320-x] [PMID: 25652245]
[91]
Lorca, R.; Velasco, E.; Madera, J.; Fidalgo, A.; Alonso-Arias, R.; del Valle, R.; Rozado, J.; Morís, C. Kounis syndrome: Identifying the trigger. Int. J. Cardiol., 2016, 209, 179-180.
[http://dx.doi.org/10.1016/j.ijcard.2016.02.079] [PMID: 26896617]
[92]
Hamera, L.; Khishfe, B.F. Kounis syndrome and ziprasidone. Am. J. Emerg. Med., 2017, 35(3), 493-494.
[http://dx.doi.org/10.1016/j.ajem.2016.11.061] [PMID: 27919473]
[93]
Salouage, I.; El Aidli, S.; Kastalli, S.; Daghfous, R.; Lakhal, M. Fatal Kounis syndrome with stent thrombosis secondary to amoxicillin/clavulanic acid use: A case report and literature review. Therapie, 2016, 71(6), 535-539.
[http://dx.doi.org/10.1016/j.therap.2016.06.004] [PMID: 27692979]
[94]
Keskin, M.; Hayıroğlu, M.I.; Onuk, T.; Keskin, Ü.; Ekmekçi, A. Kounis syndrome presenting with acute inferior wall myocardial infarction and cardiogenic shock secondary to intravenous ampicillin/sulbactam administration. Anatol. J. Cardiol., 2016, 16(11), 893-894.
[http://dx.doi.org/10.14744/AnatolJCardiol.2016.7335] [PMID: 27872436]
[95]
Terzioğlu, K.; Ediger, D.; Tülümen Öztürk, R.; Durmuş, E.; Alışır, M.F. Kounis syndrome not induced but prevented by the implantation of a drug-eluting stent: A case report. Anatol. J. Cardiol., 2017, 17(5), 412-413.
[http://dx.doi.org/10.14744/AnatolJCardiol.2017.7690] [PMID: 28529288]
[96]
Kitulwatte, I.D.G.; Gangahawatte, S.; Perera, U.L.M.S.; Edirisinghe, P.A.S. Death following ceftazidime-induced Kounis syndrome. Med. Leg. J., 2017, 85(4), 215-218.
[http://dx.doi.org/10.1177/0025817217695904] [PMID: 29210337]
[97]
Mitsis, A.; Christodoulou, E.; Georgiou, P. Coronary spasm secondary to cefuroxime injection, complicated with cardiogenic shock : A manifestation of Kounis syndrome: Case report and literature review. Eur. Heart J. Acute Cardiovasc. Care, 2018, 7(7), 624-630.
[http://dx.doi.org/10.1177/2048872617701885] [PMID: 28345355]
[98]
Omri, M.; Kraiem, H.; Mejri, O.; Naija, M.; Chebili, N. Management of Kounis syndrome: Two case reports. J. Med. Case Rep., 2017, 11(1), 145.
[http://dx.doi.org/10.1186/s13256-017-1310-7] [PMID: 28532437]
[99]
Canpolat, U.; Koçyiğit, D.; Aytemir, K. Interesting presentation of Kounis syndrome secondary to amoxicillin/clavulanate use: Coronary vasospasm and simultaneous appropriate implantable defibrillator shock. Turk Kardiyol. Dern. Ars., 2017, 45(5), 466-469.
[http://dx.doi.org/10.5543/tkda.2017.38845] [PMID: 28694403]
[100]
Antonelli, D.; Rozner, E.; Turgeman, Y. Kounis syndrome: Acute ST segment elevation myocardial infarction following allergic reaction to amoxicillin. Isr. Med. Assoc. J., 2017, 19(1), 59-60.
[PMID: 28457118]
[101]
Akçay, M. Ibuprofen-induced Kounis syndrome with diffuse ST segment depression and atrial fibrillation. Anatol. J. Cardiol., 2017, 18(5), 380-381.
[http://dx.doi.org/10.14744/AnatolJCardiol.2017.8045] [PMID: 29145229]
[102]
El Hangouche, A.J.; Lamliki, O.; Oukerraj, L.; Dakka, T.; Doghmi, N.; Zarzur, J.; Cherti, M. Kounis syndrome induced by oral intake of aspirin: Case report and literature review. Pan Afr. Med. J., 2018, 30, 301.
[http://dx.doi.org/10.11604/pamj.2018.30.301.14948] [PMID: 30637085]
[103]
Sciatti, E.; Vizzardi, E.; Cani, D.S.; Castiello, A.; Bonadei, I.; Savoldi, D.; Metra, M.; D’Aloia, A. Kounis syndrome, a disease to know: Case report and review of the literature. Monaldi Arch. Chest Dis., 2018, 88(1), 898.
[http://dx.doi.org/10.4081/monaldi.2018.898] [PMID: 29557575]
[104]
Ricciardi, L.; Furci, F.; Casciaro, M.; Di Salvo, E.; Cristani, M.; Tigano, V.; Minciullo, P.L.; Gangemi, S. Drug induced Kounis syndrome: Does oxidative stress play a role? Clin. Mol. Allergy, 2018, 16(1), 21.
[http://dx.doi.org/10.1186/s12948-018-0099-2] [PMID: 30305804]
[105]
Pradhan, S.; Christ, M.; Trappe, H.J. Kounis syndrome induced by amoxicillin following vasospastic coronary event in a 22-year-old patient: a case report. Cardiovasc. Diagn. Ther., 2018, 8(2), 180-185.
[http://dx.doi.org/10.21037/cdt.2018.03.07] [PMID: 29850410]
[106]
Absmaier, M.; Biedermann, T.; Brockow, K. Allergic myocardial infarction (Kounis syndrome) after cefuroxime with side-chain cross-reactivity. J. Allergy Clin. Immunol. Pract., 2018, 6(5), 1781-1783.e1.
[http://dx.doi.org/10.1016/j.jaip.2018.01.033] [PMID: 29428243]
[107]
Özlek, B.; Özlek, E.; Çelik, O.; Çil, C.; Doğan, V.; Biteker, M. Allergic myocardial infarction following recombinant human insulin. Heart Lung, 2018, 47(4), 360-362.
[http://dx.doi.org/10.1016/j.hrtlng.2018.03.014] [PMID: 29709318]
[108]
Özlek, E.; Biteker, F.S.; Çelik, O.; Özlek, B.; Çil, C.; Biteker, M. Gemifloxacin-induced allergic myocardial infarction: A case report. J. Emerg. Med., 2019, 56(6), e103-e105.
[http://dx.doi.org/10.1016/j.jemermed.2019.03.001] [PMID: 31003822]
[109]
Akçay, M.; Yüksel, S. Isotretinoin-associated possible Kounis syndrome: A case report and a review of other cardiovascular side effects reported in the literature. Turk Kardiyol. Dern. Ars., 2018, 47(4), 324-328.
[http://dx.doi.org/10.5543/tkda.2018.67055] [PMID: 31219450]
[110]
O’Connor, R.D.; Hofland, E.; Latten, G.; Pluijms, W.A.; Ruiters, A.W.; Hoofwijk, D. Kounis syndrome, the allergic acute coronary syndrome. Ned. Tijdschr. Geneeskd., 2019, 163, D3250.
[PMID: 31050277]
[111]
Maloberti, A.; Pansera, F.; Sala, O.; Fusco, R.; Pierri, A.; Bossi, I.; Giannattasio, C. Kounis syndrome: Report of two cases with peculiar presentation and diagnostic issues. High Blood Press. Cardiovasc. Prev., 2019, 26(2), 145-149.
[http://dx.doi.org/10.1007/s40292-019-00312-w] [PMID: 30912004]
[112]
Fujisaki, T.; Higa, T.; Uechi, Y.; Maehira, N. A case report of Kounis syndrome presenting with a rash, very late stent thrombosis and coronary evaginations. Eur. Heart J. Case Rep., 2020, 4(1), 1-5.
[http://dx.doi.org/10.1093/ehjcr/ytaa002] [PMID: 33123674]
[113]
Ishikura, M.; Endo, A.; Sakamoto, T.; Tanabe, J.; Okazaki, K.; Ouchi, T.; Watanabe, N.; Tanabe, K. Clarithromycin-induced coronary vasospasms caused acute coronary syndrome in a 19-year-old male patient. Intern. Med., 2021, 60(2), 281-285.
[http://dx.doi.org/10.2169/internalmedicine.5548-20] [PMID: 32963159]
[114]
Zakka, K.; Gadi, S.; Koshlelashvili, N.; Maleque, N.M. Acute myocardial injury after administration of intravenous epinephrine for allergic reaction. SAGE Open Med. Case Rep., 2020, 8, 2050313X2093310.
[http://dx.doi.org/10.1177/2050313X20933104] [PMID: 32595973]
[115]
Wu, H.; Cao, Y.; Chang, F.; Zhang, C.; Hu, Y.; Liang, L. Kounis syndrome induced by anisodamine: A case report. Int. J. Gen. Med., 2020, 13, 1523-1527.
[http://dx.doi.org/10.2147/IJGM.S289015] [PMID: 33363401]
[116]
Custódio, J.V.; Guimarães, P.O.; Tonin, M.H.L.; Sampaio, M.C.; Malafaia, F.L.; de Souza Brito, F.; de Barros e Silva, P.G.M.; Furlan, V. Acute coronary syndrome after ondansetron administration in a pregnant woman. JACC. Case Rep., 2020, 2(1), 6-8.
[http://dx.doi.org/10.1016/j.jaccas.2019.11.051] [PMID: 34316955]
[117]
Çakmak, A.; Keskin, G. Kounis syndrome: Is ceftriaxone or metronidazole responsible for acute myocardial infarction? A rare case. Anatol. J. Cardiol., 2021, 25(6), 451-452.
[http://dx.doi.org/10.5152/AnatolJCardiol.2020.36422] [PMID: 34100733]
[118]
Miura, S.; Yamashita, T.; Murata, M.; Kounis, N.G. Uncommon but imperative cause of repeated acute stent thrombosis: Kounis syndrome type III. BMJ Case Rep., 2021, 14(3), e240704.
[http://dx.doi.org/10.1136/bcr-2020-240704] [PMID: 33649028]
[119]
Aksakal, A.; Simşek, Z.; Köprülü, D.; Arslan, U. Kounis syndrome: Dexketoprofen-associated ST-elevation myocardial infarction. Eur. J. Case Rep. Intern. Med., 2021, 8(11), 16.
[http://dx.doi.org/10.12890/2021_003006] [PMID: 34912743]
[120]
Liang, H.; Zhao, H.; Gao, J.; Cao, C.; Wang, W. Epirubicin-induced Kounis syndrome. BMC Cardiovasc. Disord., 2021, 21(1), 133.
[http://dx.doi.org/10.1186/s12872-021-01936-4] [PMID: 33711934]
[121]
Karunathilake, P.; Ralapanawa, U.; Jayalath, T.; Abeyagunawardena, S. Kounis syndrome secondary to medicine-induced hypersensitivity. Case Rep. Med., 2021, 2021, 1-6.
[http://dx.doi.org/10.1155/2021/4485754] [PMID: 34630571]
[122]
Wu, H.Y.; Gao, T.J.; Cao, Y.W.; You, P.H. Case Report: Phloroglucinol-induced Kounis syndrome. Front. Cardiovasc. Med., 2021, 8, 668318.
[http://dx.doi.org/10.3389/fcvm.2021.668318] [PMID: 34012985]
[123]
Yamashita, T.; Oguma, Y.; Kounis, N.G. Kounis syndrome: Kill two birds with one stone. J. Invasive Cardiol., 2021, 33(11), E920-E921.
[PMID: 34735359]
[124]
Gogos, C.; Sachpekidis, V.; Moschovidis, V.; Styliadis, I.; Kounis, N.G. Kounis syndrome in a COVID-19 patient following intravenous administration of azithromycin. J. Investig. Allergol. Clin. Immunol., 2022, 32(1), 75-76.
[http://dx.doi.org/10.18176/jiaci.0723] [PMID: 34156959]
[125]
Diaz-Rodriguez, P.E.; Molina-Lopez, V.H.; Gonzalez Burgos, B.A.; Nieves-La Cruz, C. A Rare Case of Kounis syndrome secondary to infliximab. Cureus, 2023, 15(9), e44704.
[http://dx.doi.org/10.7759/cureus.44704] [PMID: 37809202]
[126]
Sagalov, A.; Eggert, A.; Rimawi, A.; Hegde, S. A rare presentation of Kounis syndrome induced by an echocardiography contrast. CJC Open, 2023, 5(10), 757-759.
[http://dx.doi.org/10.1016/j.cjco.2023.07.009] [PMID: 37876888]
[127]
Soufras, G.D.; Ginopoulos, P.V.; Papadaki, P.J.; Zavras, G.M.; Gouvelou-Deligianni, G.V.; Batsolaki, M.; Kouni, S.; Kounis, N.G.; Koutsojannis, C.M. Penicillin allergy in cancer patients manifesting as Kounis syndrome. Heart Vessels, 2005, 20(4), 159-163.
[http://dx.doi.org/10.1007/s00380-004-0804-6] [PMID: 16025365]
[128]
Dauvergne, C.; Araya, M.; Abufhele, A. Coronary spasm secondary to an allergic reaction or Kounis syndrome: Report of one case. Rev. Med. Chil., 2009, 137(6), 811-814.
[PMID: 19746284]
[129]
Kocabay, G.; Karabay, C.Y.; Kounis, N.G. Myocardial infarction secondary to contrast agent. Contrast effect or type II Kounis syndrome? Am. J. Emerg. Med., 2012, 30(1), 255.e1-255.e2.
[http://dx.doi.org/10.1016/j.ajem.2010.10.012] [PMID: 21159465]
[130]
Abusnina, W.; Shehata, M.; Abouzid, M.; Price, M.; Zeid, F. Kounis syndrome secondary to gadolinium contrast agent. Proc. Bayl. Univ. Med. Cent., 2019, 32(2), 253-255.
[http://dx.doi.org/10.1080/08998280.2019.1581319] [PMID: 31191145]
[131]
Choudhry, F.; Fackler, M.; Patel, M.; Patel, V.; Arnautovic, J. The unusual suspect: Gadobenate-dimeglumine induced Kounis syndrome. Spartan Med. Res. J., 2019, 4(1), 8999.
[http://dx.doi.org/10.51894/001c.8999] [PMID: 33655161]
[132]
Portero-Portaz, J.J.; Córdoba-Soriano, J.G.; Gallego-Page, J.C.; Type, I.I.I. Type III Kounis syndrome after administration of an echocardiography contrast agent. Eur. Heart J. Acute Cardiovasc. Care, 2020, 9(6), NP1-NP2.
[http://dx.doi.org/10.1177/2048872616655943] [PMID: 27325844]
[133]
de Groot, J.W.B.; Gosselink, A.T.M.; Ottervanger, J.P. Acute ST-segment elevation myocardial infarction associated with diclofenac-induced anaphylaxis: Case report. Am. J. Crit. Care, 2009, 18(4), 388-386, 386-387.
[http://dx.doi.org/10.4037/ajcc2009100] [PMID: 19556418]
[134]
Elsayed, Y.M.H. Diclofenac potassium-induced anaphylaxis with an allergic acute coronary syndrome and premature ventricular contractions; outpatient clinic management : A case report. Rea. Int. J. Card. Cardio., 2020, 1(1), 013-016.
[http://dx.doi.org/10.37179/rijccm.000005]
[135]
Yanagawa, Y.; Jitsuiki, K.; Kushida, Y.; Morohashi, I. Repeated anaphylactic reaction after walking following an intraarticular injection of diclofenac etalhyaluronate sodium during a 3-day period. Acute Med. Surg., 2022, 9(1), e729.
[http://dx.doi.org/10.1002/ams2.729] [PMID: 35223043]
[136]
Firew, E.; Huang, H.; Anand, A.; Asfaw, Y.A.; Parikh, C.; Khan, H.R. Ondansetron-induced pseudoallergy with non-ischemic myocardial injury: A rare case report of Kounis syndrome. Clin. Case Rep., 2022, 10(12), e6781.
[http://dx.doi.org/10.1002/ccr3.6781] [PMID: 36578798]
[137]
González-de-Olano, D.; Gandolfo-Cano, M.; Mohedano-Vicente, E.; González-Mancebo, E.; Matito, A.; Kounis, N.G.; Escribano, L. Kounis syndrome following the performance of skin test to amoxicillin. Int. J. Cardiol., 2014, 174(3), 856-857.
[http://dx.doi.org/10.1016/j.ijcard.2014.04.191] [PMID: 24801079]
[138]
Franco Hernández, J.A.; García Hernández, A.; Lahoz Rodríguez, D. Kounis syndrome secondary to an allergic reaction to metamizole. Rev. Esp. Anestesiol. Reanim., 2012, 59(4), 217-219.
[http://dx.doi.org/10.1016/j.redar.2012.02.012] [PMID: 22559993]
[139]
Regis, A.C.; Germann, C.A.; Crowell, J.G. Myocardial infarction in the setting of anaphylaxis to celecoxib: A case of Kounis syndrome. J. Emerg. Med., 2015, 49(2), e39-e43.
[http://dx.doi.org/10.1016/j.jemermed.2015.02.044] [PMID: 25989969]
[140]
Liping, Z.; Bin, H.; Qiming, F. An extraordinary case associated with an allergic reaction to clopidogrel: Coronary artery spasm or Kounis syndrome? Heart Lung Circ., 2015, 24(11), e180-e183.
[http://dx.doi.org/10.1016/j.hlc.2015.04.183] [PMID: 26138623]
[141]
Lerner, M.; Pal, R.S.; Borici-Mazi, R. Kounis syndrome and systemic mastocytosis in a 52-year-old man having surgery. CMAJ, 2017, 189(5), E208-E211.
[http://dx.doi.org/10.1503/cmaj.151314] [PMID: 27486207]
[142]
Molina Anguita, M.; García Rodríguez, C.; Méndez Díaz, Y.; Galindo Bonilla, P.A. Kounis syndrome: A diagnostic urgency. Semergen, 2016, 42(7), e133-e135.
[http://dx.doi.org/10.1016/j.semerg.2015.11.007] [PMID: 26831543]
[143]
Arora, S.; Patel, R.; Fadila, M.; Wool, K. The atopic heart: A curious case of coronary hypersensitivity. Neth. J. Med., 2016, 74(3), 130-132.
[PMID: 27020993]
[144]
Gao, J.; Gao, Y.; Ma, J. Cefuroxime-associated Kounis syndrome with unique peculiarity in perioperative prophylaxis. J. Infect. Public Health, 2018, 11(6), 889-892.
[http://dx.doi.org/10.1016/j.jiph.2018.02.009] [PMID: 29534969]
[145]
Despotopoulos, S.; Roumeliotis, A.; Kounis, N.G.; Tsigkas, G.; Hahalis, G.; Davlouros, P. Severe allergic reaction during angioplasty culminating to fatal acute stent thrombosis: An association with Kounis syndrome. Heart Lung, 2019, 48(2), 138-140.
[http://dx.doi.org/10.1016/j.hrtlng.2018.07.015] [PMID: 30245248]
[146]
Boucher, T.; Shah, A.M.; Hashim, H.; Jerschow, E.; Bortnick, A.E. Durable polymer drug eluting stent-induced Kounis syndrome and eosinophilia requiring long-term immunosuppression. Can. J. Cardiol., 2022, 38(3), 398-400.
[http://dx.doi.org/10.1016/j.cjca.2021.12.001] [PMID: 34902455]
[147]
Shrimanth, Y.S.; Vemuri, K.S.; Gawalkar, A.A.; Ghosh, S.; Vijay, J.; Prarthana, T.; Sihag, B.K. Kounis syndrome secondary to nimesulide ingestion: A case report. Egypt. Heart J., 2021, 73(1), 106.
[http://dx.doi.org/10.1186/s43044-021-00233-x] [PMID: 34928466]
[148]
Kogias, J.S.; Papadakis, E.X.; Tsatiris, C.G.; Hahalis, G.; Kounis, G.N.; Mazarakis, A.; Batsolaki, M.; Gouvelou-Deligianni, G.V.; Kounis, N.G. Kounis syndrome: A manifestation of drug-eluting stent thrombosis associated with allergic reaction to contrast material. Int. J. Cardiol., 2010, 139(2), 206-209.
[http://dx.doi.org/10.1016/j.ijcard.2008.08.026] [PMID: 18805597]
[149]
Obata, A.; Saito-Sasaki, N.; Sugino, H.; Itamura, M.; Okada, E.; Sawada, Y. Cardiac arrest due to Kounis syndrome following cephazolin administration during surgery under local anesthesia. Cureus, 2023, 15(9), e46297.
[http://dx.doi.org/10.7759/cureus.46297] [PMID: 37915873]
[150]
Sánchez, V.O.; Roca, L.C.; Moreno, A.P. Intraoperative Kounis syndrome that improved electrocardiography changes and hemodynamic situation after administering nitroglycerine. Braz. J. Anesthesiol., 2014, 64(4), 281-285.
[http://dx.doi.org/10.1016/j.bjane.2013.06.015] [PMID: 24998115]
[151]
Juste, J.F.M.; Garces, T.R.; Enguita, R.G.; Blasco, P.C.; Trallero, J.A. Cardiac complications in a metamizole-induced type I Kounis syndrome. Braz. J. Anesthesiol., 2016, 66(2), 194-196.
[http://dx.doi.org/10.1016/j.bjan.2013.07.008] [PMID: 26952229]
[152]
Cuesta, J.; Bastante, T.; Rivero, F.; Benedicto, A.; Pérez, I.T.; Tur, N.; Alfonso, F. Kounis syndrome: Optical coherence tomography findings. Int. J. Cardiol., 2015, 182, 242-243.
[http://dx.doi.org/10.1016/j.ijcard.2014.12.082] [PMID: 25577771]
[153]
Sato, M.; Arai, T. A case of Kounis syndrome presenting as coronary artery spasm associated with cefazolin-induced anaphylaxis during general anesthesia. JA Clin. Rep., 2019, 5(1), 49.
[http://dx.doi.org/10.1186/s40981-019-0269-3] [PMID: 32026020]
[154]
Duarte, P.; Costa, J.; Serena, C.; Almeida, C.; Gouveia, S.; Lourenço, C.; Costa, H.; Paiva, C. Kounis syndrome. Apropos of a clinical case. Rev. Bras. Ter. Intensiva, 2020, 32(1), 149-152.
[http://dx.doi.org/10.5935/0103-507X.20200021] [PMID: 32401974]
[155]
Lee Chuy, K.; Reddy, P.R.; Vij, A. Recurrent coronary vasospasm: A case of Kounis syndrome from anaphylaxis to contrast dye. Methodist DeBakey Cardiovasc. J., 2022, 18(1), 29-36.
[http://dx.doi.org/10.14797/mdcvj.1084] [PMID: 35855403]
[156]
Nojima, Y.; Adachi, H.; Ihara, M.; Nanto, S.; Type, I.I. Type II Kounis syndrome diagnosed by optical coherence tomography and coronary angioscopy. Cardiol. J., 2023, 30(1), 157-158.
[http://dx.doi.org/10.5603/CJ.2023.0010] [PMID: 36861932]
[157]
Chien, D.S.; Tsai, A.P.Y.; Lin, P.C.; Yiang, G.T.; Wu, M.Y. Contrast media induced Kounis syndrome: A case report. Diagnostics, 2019, 9(4), 154.
[http://dx.doi.org/10.3390/diagnostics9040154] [PMID: 31635242]
[158]
Rajh, F.; Raja, R.; Rajah, F.; AlAli, A. Acute ST-segment elevation myocardial infarction following intramuscular diclofenac: A case of Kounis syndrome. J. Emerg. Med., 2019, 57(1), e5-e8.
[http://dx.doi.org/10.1016/j.jemermed.2019.03.026] [PMID: 31014971]
[159]
Palacios-Zabalza, I.; Camino-Rodríguez, E.; Aguirre, C. Kounis syndrome induced by ranitidine. Med. Clín., 2018, 151(9), e51-e53.
[http://dx.doi.org/10.1016/j.medcli.2018.02.006] [PMID: 29525117]
[160]
Ding, P.; Zhou, Y.; Long, K.; Zhang, L.; Gao, P. Case report: Cefoperazone-sulbactam induced Kounis syndrome and cardiogenic shock. Front. Cardiovasc. Med., 2022, 9, 1061586.
[http://dx.doi.org/10.3389/fcvm.2022.1061586] [PMID: 36465467]
[161]
Rodríguez-Serrano, D.A.; Torrejón-Pérez, I.; Abella-Álvarez, A.; Elices, A. Kounis syndrome type I. Rev. Clin. Esp., 2012, 212(9), 472-473.
[http://dx.doi.org/10.1016/j.rce.2011.10.008] [PMID: 22153584]
[162]
Kılıc, D.; Evrengül, H.; Ozcan, A.V.; Tanriverdi, H.; Caglıyan, O.; Kaftan, A. Acute ST segment elevation myocardial infarction after sulbactam–ampicilllin induced anaphylactic shock in an adult with significant coronary artery disease: A case report. Int. J. Cardiol., 2009, 135(1), e30-e33.
[http://dx.doi.org/10.1016/j.ijcard.2008.03.069] [PMID: 18632173]
[163]
Rayner-Hartley, E.; Chou, A.; Saw, J.; Sedlak, T. A case of kounis type I in a young woman with samter’s triad. Can. J. Cardiol., 2016, 32(10), 1261.e1-1261.e3.
[http://dx.doi.org/10.1016/j.cjca.2015.12.012] [PMID: 26947537]
[164]
Singh Mahal, H. Fluconazole-Induced Type 1 Kounis syndrome. Am. J. Ther., 2016, 23(3), e961-e962.
[http://dx.doi.org/10.1097/MJT.0000000000000113] [PMID: 26938747]
[165]
Kim, H.I.; Cha, K.C.; Cha, Y.S.; Kim, O.H.; Kim, H.; Lee, K.H.; Ahn, M.S.; Lee, J.W.; Hwang, S.O. A subset of type I variant Kounis syndrome: Allergic angina syndrome and persistent presence of coronary spasm. Int. J. Cardiol., 2016, 223, 959-961.
[http://dx.doi.org/10.1016/j.ijcard.2016.08.247] [PMID: 27589045]
[166]
Almeida, J.; Ferreira, S.; Malheiro, J.; Fonseca, P.; Caeiro, D.; Dias, A.; Ribeiro, J.; Gama, V. A rare cause of acute coronary syndrome: Kounis syndrome. Rev. Port. Cardiol., 2016, 35(12), 699.e1-699.e4.
[http://dx.doi.org/10.1016/j.repc.2016.03.009] [PMID: 27865673]
[167]
Adachi, H.; Ihara, M.; Nojima, Y.; Kurimoto, T.; Nanto, S. Kounis syndrome caused by anaphylaxis without skin manifestations after cefazolin administration. J. Allergy Clin. Immunol. Pract., 2019, 7(1), 317-319.
[http://dx.doi.org/10.1016/j.jaip.2018.05.030] [PMID: 29902529]
[168]
Mendoza Vásquez, L.E. Allergic acute coronary syndrome (Kounis syndrome) in a young woman during spinal anesthesia: A case report. A A Pract., 2018, 11(6), 155-157.
[http://dx.doi.org/10.1213/XAA.0000000000000768] [PMID: 29621013]
[169]
Wang, B.; Sethwala, A.; Gurvitch, R. Type 1 Kounis syndrome after paclitaxel infusion in a patient treated for lung adenocarcinoma. Intern. Med. J., 2021, 51(3), 448-449.
[http://dx.doi.org/10.1111/imj.15226] [PMID: 33738953]
[170]
Vu, V.H.; Nguyen, K.D.; Nguyen, C.D.; Truong, B.Q. A Case of Kounis syndrome presenting as coronary artery spasm associated with acetaminophen infusion. Am. J. Case Rep., 2021, 22, e934190.
[http://dx.doi.org/10.12659/AJCR.934190] [PMID: 34807902]
[171]
Tanaka, H.; Urushima, M.; Hirano, S.; Takenaga, M. An acute adverse reaction with ST elevation induced by magnetic resonance contrast media: Kounis syndrome. Intern. Med., 2019, 58(2), 243-245.
[http://dx.doi.org/10.2169/internalmedicine.0802-18] [PMID: 30146563]
[172]
Amino, M.; Fukushima, T.; Uehata, A.; Nishikawa, C.; Morita, S.; Nakagawa, Y.; Murakami, T.; Yoshioka, K.; Ikari, Y. Should beta-blockers be continued as a treatment for myocardial infarction in the case of Kounis syndrome? Ann. Noninvasive Electrocardiol., 2021, 26(4), e12837.
[http://dx.doi.org/10.1111/anec.12837] [PMID: 33783917]
[173]
Akgullu, C.; Eryilmaz, U.; Gungor, H.; Zencir, C.; Selvi, M.; Avcil, M.; Dagli, B. Myocardial infarction secondary to morphine-induced Kounis syndrome. Herz, 2014, 39(7), 874-876.
[http://dx.doi.org/10.1007/s00059-013-3919-7] [PMID: 23907697]
[174]
Shimi, A.; Touzani, S.; Derkaoui, A.; Khatouf, M. Kounis syndrome associated with amoxicillin/clavulanic acid. Saudi J. Anaesth., 2016, 10(4), 444-445.
[http://dx.doi.org/10.4103/1658-354X.177329] [PMID: 27833491]
[175]
Gluvic, Z.; Putniković, B.; Panic, M.; Stojkovic, A.; Rasic-Milutinovic, Z.; Jankovic-Gavrilovic, J. Acute coronary syndrome in diclofenac sodium-induced type i hypersensitivity reaction: Kounis syndrome. Malta Med. J., 2007, 19, 36-39.
[176]
Cagliyan, C.E.; Balli, M.; Tekin, K.; Turkmen, S.; Tanboga, İ.H. Kounis syndrome triggered by diclofenac sodium injection which leads to myocardial infarction and cardiac arrest. J. Cardiol. Cases, 2013, 8(1), e17-e19.
[http://dx.doi.org/10.1016/j.jccase.2013.03.002] [PMID: 30546731]
[177]
Ichinomiya, T.; Sekino, M.; Toba, M.; Yokoyama, A.; Iwasaki, N.; Kasai, Y.; Araki, H.; Yano, R.; Matsumoto, S.; Kurobe, M.; Sasaki, R.; Hara, T. Refractory cardiac arrest caused by type I Kounis syndrome treated with adrenaline and nicorandil: A case report. Medicine, 2023, 102(32), e34535.
[http://dx.doi.org/10.1097/MD.0000000000034535] [PMID: 37565887]
[178]
Yu, H.K.; Park, M.; Lee, S.H.; Woo, J.W.; Kang, D.H.; Byun, J.H.; Ok, S.H. Early Use of ECMO for Refractory Kounis syndrome concealed by general anesthesia : A case report. Medicina, 2022, 58(6), 759.
[http://dx.doi.org/10.3390/medicina58060759] [PMID: 35744022]
[179]
Itoh, T.; Kanaya, Y.; Komuro, K.; Sugawara, S.; Ishikawa, Y.; Onodera, M.; Goto, I.; Fusazaki, T.; Nakamura, M. Kounis syndrome caused by protamine shock after coronary intervention: A case report. J. Cardiol. Cases, 2022, 25(1), 23-25.
[http://dx.doi.org/10.1016/j.jccase.2021.06.001] [PMID: 35024063]
[180]
Fagley, R.E.; Woodbury, A.; Visuara, A.; Wall, M. Rocuronium-induced coronary vasospasm Kounis syndrome. Int. J. Cardiol., 2009, 137(2), e29-e32.
[http://dx.doi.org/10.1016/j.ijcard.2008.05.052] [PMID: 18804883]
[181]
Yang, Y.L.; Huang, H.W.; Yip, H.K.; Jawan, B.; Tseng, C.C.; Lu, H.F. Acute coronary syndrome in cisatracurium-induced anaphylactic shock: Kounis syndrome. Acta Anaesthesiol. Taiwan., 2008, 46(4), 184-186.
[http://dx.doi.org/10.1016/S1875-4597(09)60007-2] [PMID: 19097966]
[182]
Tanboğa, İ.H.; Karabay, C.Y.; Can, M.M.; Akgün, T.; Güler, A.; Turkylmaz, E.; Özveren, O.; Kaymaz, C. Kounis syndrome presenting with cardiogenic shock. J. Cardiovasc. Med., 2011, 12(11), 833-836.
[http://dx.doi.org/10.2459/JCM.0b013e32833b97a9] [PMID: 20543709]
[183]
Shah, G.; Scadding, G.; Nguyen-Lu, N.; Wigmore, T.; Chenzbraun, A.; Wechalekar, K.; Sharma, R.; Lyon, A.R. Peri-operative cardiac arrest with ST elevation secondary to gelofusin anaphylaxis Kounis syndrome in the anaesthetic room. Int. J. Cardiol., 2013, 164(3), e22-e26.
[http://dx.doi.org/10.1016/j.ijcard.2012.09.166] [PMID: 23141553]
[184]
Yoon, S.H.; Bang, J.Y.; Seo, H.; Song, J.G. Sudden cardiovascular collapse caused by severe anaphylaxis after cisatracurium use: A case report. Korean J. Anesthesiol., 2014, 67(6), 412-415.
[http://dx.doi.org/10.4097/kjae.2014.67.6.412] [PMID: 25558342]
[185]
Kido, K.; Adams, V.R.; Morehead, R.S.; Flannery, A.H. Capecitabine-induced ventricular fibrillation arrest: Possible Kounis syndrome. J. Oncol. Pharm. Pract., 2016, 22(2), 335-340.
[http://dx.doi.org/10.1177/1078155214563814] [PMID: 25870182]
[186]
de la Fuente Tornero, E.; Vega Castro, A.; de Sierra Hernández, P.Á.; Balaguer Recena, J.; Zaragoza Casares, S.C.; Serrano Baylin, F.M.; Gallardo Culebradas, P.; Amorós Alfonso, B.; Rodríguez Fraile, J.R. Kounis syndrome during anesthesia. A A Case Rep., 2017, 8(9), 226-228.
[http://dx.doi.org/10.1213/XAA.0000000000000474] [PMID: 28181948]
[187]
Yanai, M.; Ariyoshi, K. Two cardiac arrests that occurred after the administration of sugammadex: A case of Kounis syndrome. Case Rep. Emerg. Med., 2020, 2020, 1-4.
[http://dx.doi.org/10.1155/2020/6590101] [PMID: 32128264]
[188]
Caragnano, V.; Distaso, S.; Scicchitano, P.; Chieppa, D.R.R.; Liotino, M.; Scialpi, A.; Malerba, L.; Panunzio, M.; Rosa, I.; Musaico, F.; Massari, V.; Fracchiolla, M.; Scardigno, A.D.; Deluca, G.; Modugno, G.; Ciccone, M.M. Cardiac arrest in type II Kounis syndrome after oral intake of amoxicilline. Am. J. Cardiovasc. Dis., 2020, 10(3), 195-200.
[PMID: 32923101]
[189]
Yanagawa, Y.; Tajima, M.; Ohara, K.; Aihara, K.; Matsuda, S.; Iba, T. A case of cardiac arrest with ST elevation induced by contrast medium. Am. J. Emerg. Med., 2012, 30(9), 2083.e3-2083.e4.
[http://dx.doi.org/10.1016/j.ajem.2011.11.011] [PMID: 22177586]
[190]
Kumaran, T.; Damodaran, S.; Singh, A.P.; Kanchi, M. Intraoperative cardiac arrest due to allergic acute coronary syndrome (Kounis syndrome) triggered by cephalosporin. Ann. Card. Anaesth., 2023, 26(2), 219-222.
[http://dx.doi.org/10.4103/aca.aca_302_20] [PMID: 37706392]
[191]
İbrahim, A.; Çolak, Ş.; Erdoğan, M.Ö.; Afacan, M.A.; Sarıtaş, A.; Kandiş, H. Kounis syndrome as a result of anaphylactic reaction to diclofenac sodium: A case report. J. Surg. Med., 2018, 2, 337-338.
[http://dx.doi.org/10.28982/josam.402775]
[192]
García Núñez, I.; Algaba Mármol, M.A.; Barasona Villarejo, M.J.; Suárez Vergara, M.; Espínola González, F.; Reina Ariza, E. Kounis syndrome after levofloxacin intake: A clinical report and cross-reactivity study. J. Investig. Allergol. Clin. Immunol., 2016, 26(5), 335-336.
[http://dx.doi.org/10.18176/jiaci.0091] [PMID: 27763868]
[193]
Forlani, D.; Scarano, G.; D’Alleva, A.; Di Marco, M.; Paloscia, L.; Gatta, A.; Della Valle, L.; Farinelli, A.; Lumaca, A.; Petrarca, C.; Paganelli, R.; Di Giampaolo, L.; Di Gioacchino, M. Kounis syndrome as first manifestation of allergic sensitization. Case Rep. Med., 2019, 2019, 1-5.
[http://dx.doi.org/10.1155/2019/6317956] [PMID: 31341482]
[194]
Zlojtro, M.; Roginic, S.; Nikolic-Heitzler, V.; Babic, Z.; Kaliterna, D.M.; Marinko, A. Kounis syndrome: Simultaneous occurrence of an allergic reaction and myocardial ischemia in a 46 year old patient after administration of contrast agent. Isr. Med. Assoc. J., 2013, 15(11), 725-726.
[PMID: 24511660]
[195]
Bhaskaran, A.; Deshmukh, T.; Sivagangabalan, G. Intraprocedure Type II Kounis syndrome secondary to radioiodine contrast during coronary angiography. Can. J. Cardiol., 2018, 34(12), 1688.e1-1688.e3.
[http://dx.doi.org/10.1016/j.cjca.2018.08.029] [PMID: 30527164]
[196]
Kerai, S.; Sehrawat, L.; Saxena, K.; Taneja, B. Occurrence of Kounis syndrome under anesthesia. J. Anaesthesiol. Clin. Pharmacol., 2017, 33(2), 276-277.
[http://dx.doi.org/10.4103/0970-9185.209737] [PMID: 28781470]
[197]
Giraldo-Tugores, M.; Sanmartín-Fernández, M.; Fernández- Lozano, C.; Martínez-Botas, J.; De-la-Hoz-Caballer, B.; González-de-Olano, D. Kounis syndrome and vanadium allergy: Heed your hunch. J. Investig. Allergol. Clin. Immunol., 2023, 33(5), 407-409.
[http://dx.doi.org/10.18176/jiaci.0884] [PMID: 36811839]
[198]
Patanè, S.; Marte, F.; Di Bella, G.; Chiofalo, S.; Currò, A.; Coglitore, S. Acute myocardial infarction and Kounis syndrome. Int. J. Cardiol., 2009, 134(2), e45-e46.
[http://dx.doi.org/10.1016/j.ijcard.2007.12.075] [PMID: 18378025]
[199]
Movva, R.; Figueredo, V.M.; Lynn Morris, D. Kounis syndrome due to angiotensin converting enzyme inhibitor. Clin. Res. Cardiol., 2013, 102(2), 163-164.
[http://dx.doi.org/10.1007/s00392-012-0504-7] [PMID: 22878733]
[200]
Hoshi, T.; Sato, A.; Akiyama, D.; Kawabe, M.; Hiraya, D.; Aonuma, K. Kounis syndrome manifesting as coronary aneurysm and very late coronary stent thrombosis. JACC Cardiovasc. Interv., 2014, 7(11), e173-e176.
[http://dx.doi.org/10.1016/j.jcin.2014.05.031] [PMID: 25459048]
[201]
Mota, I.; Gaspar, Â.; Morais-Almeida, M. Perioperative anaphylaxis including Kounis syndrome due to selective cefazolin allergy. Int. Arch. Allergy Immunol., 2018, 177(3), 269-273.
[http://dx.doi.org/10.1159/000490182] [PMID: 29913447]
[202]
Engheta, M.; Urbanczyk, J.; Fidone, E.; Escobedo, Y.; Mixon, T. Kounis syndrome presenting as ST elevation acute myocardial infarction. Proc. Bayl. Univ. Med. Cent., 2021, 34(4), 500-502.
[http://dx.doi.org/10.1080/08998280.2021.1907095] [PMID: 34219938]
[203]
Shibuya, K.; Kasama, S.; Funada, R.; Katoh, H.; Tsushima, Y. Kounis syndrome induced by contrast media: A case report and review of literature. Eur. J. Radiol. Open, 2019, 6, 91-96.
[http://dx.doi.org/10.1016/j.ejro.2019.02.004] [PMID: 30805421]
[204]
Gagnon, L.R.; Huang, Y.; Kay, R.; Cujec, B. Kounis syndrome: A case of vancomycin-associated coronary artery vasospasm resulting in myocardial infarction. CJC Open, 2022, 4(3), 337-339.
[http://dx.doi.org/10.1016/j.cjco.2021.11.003] [PMID: 35386129]
[205]
Akbaş, T.; Kaya, A.; Altun, G.; Eşbah, Ü.; Önmez, A. Cases of allergic coronary syndrome (Kounis syndrome) : What we should know. Nagoya J. Med. Sci., 2022, 84(3), 664-672.
[http://dx.doi.org/10.18999/nagjms.84.3.664] [PMID: 36237895]
[206]
Toya, T.; Kagami, K.; Adachi, T. Friend or foe: food-dependent exercise-induced anaphylaxis associated with acute coronary syndrome aggravated by adrenaline and aspirin: A case report. Eur. Heart J. Case Rep., 2019, 3(3), ytz143.
[http://dx.doi.org/10.1093/ehjcr/ytz143] [PMID: 31660504]
[207]
Urushidani, S.; Kuriyama, A. A potential association between myocardial ischemia and epinephrine for anaphylaxis. Am. J. Emerg. Med., 2020, 38(6), 1297.e1-1297.e3.
[http://dx.doi.org/10.1016/j.ajem.2020.01.033] [PMID: 31983596]
[208]
Yoshida, T.; Sumi, C.; Uba, T.; Miyata, H.; Umegaki, T.; Kamibayashi, T. A rare case of atropine-resistant bradycardia following sugammadex administration. JA Clin. Rep., 2020, 6(1), 18.
[http://dx.doi.org/10.1186/s40981-020-00326-7] [PMID: 32124089]
[209]
Sequeira, T.; Gaspar, Â.; Mota, I.; Correia, M.; Chambel, M.; Morais-Almeida, M. Kounis syndrome associated with selective anaphylaxis to cefazolin. J. Investig. Allergol. Clin. Immunol., 2018, 28(4), 257-258.
[http://dx.doi.org/10.18176/jiaci.0248] [PMID: 30073957]
[210]
Martinez, E.; Sahni, S.; Cheema, M.A.I.; Iftikhar, A. Vancomycin-induced coronary artery spasm: a case of Kounis syndrome. BMJ Case Rep., 2018, 2018, bcr-2017-222846.
[http://dx.doi.org/10.1136/bcr-2017-222846] [PMID: 29348285]
[211]
Okuno, A.; Matsuki, Y.; Tabata, M.; Shigemi, K. A suspected case of coronary vasospasm induced by anaphylactic shock caused by rocuronium-sugammadex complex. J. Clin. Anesth., 2018, 48, 7.
[http://dx.doi.org/10.1016/j.jclinane.2018.03.017] [PMID: 29660702]
[212]
del Val Villanueva, B.; Telletxea Benguria, S.; González-Larrabe, I.; Suárez Romay, J.M. Kounis syndrome after rocuronium administration. Rev. Esp. Anestesiol. Reanim., 2018, 65(6), 343-346.
[http://dx.doi.org/10.1016/j.redare.2017.12.014] [PMID: 29361310]
[213]
Cheung, M.; Seres, T.; Cleveland, J.; Kounis, N.G. Kounis syndrome, a coronary hypersensitivity disorder: A rare case of amiodarone-induced coronary vasospasm and simultaneous peripheral vasodilation intraoperatively. Int. J. Cardiol., 2016, 218, 267-268.
[http://dx.doi.org/10.1016/j.ijcard.2016.05.058] [PMID: 27236126]
[214]
Merino García, M.; Castaño Ruiz, M.; Marcos-Vidal, J.M.; González de Castro, R.; Marcos Contreras, S.; Fernández García, D. Anaphylactic shock versus Kounis syndrome in cardiac surgery: Differential diagnosis. Rev. Esp. Anestesiol. Reanim., 2019, 66(1), 53-56.
[http://dx.doi.org/10.1016/j.redare.2018.08.009] [PMID: 30290961]
[215]
Amro, M.; Mansoor, K.; Amro, A.; Okoro, K.; Okhumale, P.I. Kounis syndrome Induced by Protamine Sulfate. Cureus, 2020, 12(2), e6972.
[http://dx.doi.org/10.7759/cureus.6972] [PMID: 32190518]
[216]
Herrera-Lasso, V.; Dordal, M.T.; Alonso, G.; Camprubí, I.; Lleonart, R. Kounis syndrome due to Urapidil. J. Investig. Allergol. Clin. Immunol., 2021, 31(4), 338-340.
[http://dx.doi.org/10.18176/jiaci.0645] [PMID: 32985984]
[217]
Desai, R.; Parekh, T.; Patel, U.; Fong, H.K.; Samani, S.; Patel, C.; Savani, S.; Doshi, R.; Kumar, G.; Sachdeva, R. Epidemiology of acute coronary syndrome co-existent with allergic/hypersensitivity/anaphylactic reactions (Kounis syndrome) in the United States: A nationwide inpatient analysis. Int. J. Cardiol., 2019, 292, 35-38.
[http://dx.doi.org/10.1016/j.ijcard.2019.06.002] [PMID: 31204069]
[218]
Raschi, E.; Fertonani Affini, L.; Antonazzo, I.C.; Diemberger, I.; Poluzzi, E.; De Ponti, F. Drug-induced Kounis syndrome: A matter of pharmacovigilance. Int. J. Cardiol., 2019, 274, 381.
[http://dx.doi.org/10.1016/j.ijcard.2018.07.119] [PMID: 30057169]
[219]
Roumeliotis, A.; Davlouros, P.; Anastasopoulou, M.; Tsigkas, G.; Koniari, I.; Mplani, V.; Hahalis, G.; Kounis, N. Allergy associated myocardial infarction: A comprehensive report of clinical presentation, diagnosis and management of Kounis syndrome. Vaccines, 2021, 10(1), 38.
[http://dx.doi.org/10.3390/vaccines10010038] [PMID: 35062699]
[220]
Ollo-Morales, P.; Gutierrez-Niso, M.; De-la-Viuda-Camino, E.; Ruiz-de-Galarreta-Beristain, M.; Osaba-Ruiz-de-Alegria, I.; Martel-Martin, C. Drug-induced Kounis syndrome: Latest novelties. Curr. Treat. Options Allergy, 2023, 10(3), 301-318.
[http://dx.doi.org/10.1007/s40521-023-00342-9] [PMID: 37361641]
[221]
Castells, M.C.; Irani, A.M.; Schwartz, L.B. Evaluation of human peripheral blood leukocytes for mast cell tryptase. J. Immunol., 1987, 138(7), 2184-2189.
[http://dx.doi.org/10.4049/jimmunol.138.7.2184] [PMID: 3549898]
[222]
Kounis, N.G. Kounis syndrome: An update on epidemiology, pathogenesis, diagnosis and therapeutic management. Clin. Chem. Laborat. Med., 2016, 54(10), 1545-1559.
[http://dx.doi.org/10.1515/cclm-2016-0010] [PMID: 26966931]