Current Drug Therapy

Author(s): Imtiyaz Ahmed Najar*, Sagar Pamu, Sazal Patyar, Geetha Madhira, Akhil Sharma, Sushma Devi, Khushi Lamba, Poonam Arora and Manish Kumar*

DOI: 10.2174/0115748855310826240709062539

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Stress Management Therapy through Adaptogens and Rasayanas in Ayurveda: A Comprehensive Review

Page: [564 - 580] Pages: 17

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Abstract

This review focuses on how modern stress management incorporates Ayurvedic concepts, particularly rasayanas and adaptogens. In order to promote complete well-being, Ayurveda’s age-old holistic therapeutic method places an emphasis on mental, physical, and spiritual harmony. An imbalance of the basic bio-elements (doshas) that impacts one’s bodily and mental well-being is referred to as stress. Important components of stress treatment include rasayanas, which are reviving formulations, and adaptogens, which are herbs that boost stress tolerance. Liquorice root, Tulsi, Brahmi, Shatavari, Ashwagandha, and rasayanas like Amla and Chyawanprash constitute crucial adaptogens. The hypothalamic-pituitary-adrenal axis (a major regulator of stress response), antioxidant pathways, inflammation, and immune-mediated regulation are critically involved in the pathogenesis of stress, and all are immediately impacted by new mechanistic discoveries that lead to better alleviation of stress culminating in the initiation of a myriad of protective responses such as hepatoprotection, renoprotection, cardioprotection, and neuroprotection. Expert guidance is required to address safety issues, dosing recommendations, and specific considerations during pregnancy and nursing regarding the clinical use of these adaptogens and rasayanas. Integrating Ayurvedic concepts in modern healthcare meets problems such as standardization and quality control. However, Ayurveda’s holistic approach aligns with preventive and personalized healthcare trends. Collaborative efforts between Ayurvedic and conventional practitioners could lead to synergistic benefits. In this purview, research directions include identifying novel adaptogens, exploring mechanisms of action, and studying longterm effects and sustainability. Future studies must adopt evidence-based practices and consider Ayurveda’s individualized therapy approach. Integrating adaptogens and rasayanas in mainstream healthcare offers promising holistic strategies for stress management, aligning with the growing demand for natural and comprehensive wellness solutions.

Keywords: Ayurveda, adaptogens, rasayanas, stress management, holistic healing, HPA axis.