Abstract

This review focused on recent advances in free radical chemistry in water or aqueous media. Highlights in the progress have been made in the last decade to “tame” the reactive free radical species in aqueous phase reactions. Recent advances in several classes of widely useful free radical reactions in water have expanded the versatility and flexibility of the carbon-carbon bond formation. The review will also explore the recent advances in performing stereo-selective free radical reactions in an aqueous medium and its application in synthesis of natural and unnatural amino acids, preparation of novel materials and solid support chemistry. Some practical hints for help design high yielding free radical reactions in aqueous medium are also presented.

Keywords: free radical chemistry, aqueous media, Radical Reactions, stereo-selective, KHARASCH-TYPE PROCESSES