Generic placeholder image

Current HIV Research

Author(s): Okan Derin*, Ahsen Öncül, Hakkı Meriç Türkkan, Nazife Duygu Demirbaş, Özlem Gül, Hüsrev Diktaş, Dilek Yıldız Sevgi and Osman Hayran

DOI: 10.2174/011570162X284526240219075823

DownloadDownload PDF Flyer Cite As
Turkish Translation and Cross-Cultural Validity of WHOQOL-HIV Bref Tool

Page: [128 - 135] Pages: 8

  • * (Excluding Mailing and Handling)

Abstract

Background: The assessment of health-related quality of life among people living with HIV (PLWH) has gained increasing importance as it assesses their overall well-being, guides treatment decisions, and addresses psychosocial challenges, improving their quality of life. This study focuses on adapting and validating the Turkish version of the WHOQOL-HIV Bref, a tool developed by the World Health Organization (WHO) to measure health-related quality of life in PLWH. This adaptation is based on the generic WHOQOL-Bref Turkish and WHOQOL-HIV Bref inventory.

Methods: In line with WHO guidelines, the tool was translated and tested on 189 PLWH from İstanbul Şişli Hamidiye Etfal Training and Research Hospital's HIV outpatient clinic. A variety of statistical methods were employed to assess content, construct, concurrent, and known-group validity, as well as internal consistency and reliability.

Results: Participants' median age was 35 years (IQR: 14), with 178(94%) being male. The Turkish WHOQOL-HIV Bref showed overall satisfactory psychometric properties. Despite limitations in the spirituality domain, it demonstrated good internal consistency (alpha coefficient: 0.93) and strong validity across several metrics, including test-retest reliability (ICC: 0.79).

Conclusion: The WHOQOL-HIV BREF in Turkish is a reliable and valid instrument for assessing the quality of life in Turkish PLWH.

Graphical Abstract

[1]
Nakagawa F, Lodwick RK, Smith CJ, et al. Projected life expectancy of people with HIV according to timing of diagnosis. AIDS 2012; 26(3): 335-43.
[http://dx.doi.org/10.1097/QAD.0b013e32834dcec9] [PMID: 22089374]
[2]
Labh R, Gupta R. Emerging trends in the long-acting antiretroviral therapy: Current status and therapeutic challenges. Curr HIV Res 2021; 19(1): 4-13.
[http://dx.doi.org/10.2174/1570162X18666200824104140] [PMID: 32838720]
[3]
Lambert CC, Westfall A, Modi R, Amico RK, Golin C, Keruly J. HIV-related stigma, depression, and social support are associated with health-related quality of life among patients newly entering HIV care. AIDS Care 2019; 32(6): 681-8.
[4]
Mohammadifirouzeh M, Oh KM, Tanner S. HIV Stigma reduction interventions among health care providers and students in different countries: A systematic eeview. Curr HIV Res 2022; 20(1): 20-31.
[http://dx.doi.org/10.2174/1570162X19666211206094709] [PMID: 34872477]
[5]
Mohraz M. Sociodemographic characteristics, HIV-related risk behaviors and HIV prevalence of vulnerable men in Tehran, Iran. Curr HIV Res 2021; 19(4): 352-7.
[6]
Wolak C, Bass SB, Tedaldi E, Vandenburg-Wolf M, Rohrer C. Minority HIV patients’ perceptions of barriers and facilitators to participation in clinical research. Curr HIV Res 2012; 10(4): 348-55.
[http://dx.doi.org/10.2174/157016212800792531] [PMID: 22591357]
[7]
WHOQOL: Measuring Quality of Life. Available from: https://www.who.int/tools/whoqol/whoqol-100
[8]
WHO. Field trial WHOQOL-100 February 1995 : the 100 questions with response scales, 2012 revision 1995. Available from: https://www.who.int/publications/i/item/WHO-HIS-HSI-Rev-2012
[9]
World Health Organization. WHOQOL-HIV bref, 2012 revision. Available from: https://iris.who.int/handle/10665/77775
[10]
Ronel J, Dinkel A, Wolf E, et al. Anxiety, depression, and health-related quality of life in aging people living with HIV compared to diabetes patients and patients with minor health conditions: A longitudinal study. Psychol Health Med 2018; 23(7): 823-30.
[http://dx.doi.org/10.1080/13548506.2018.1437276] [PMID: 29430957]
[11]
Saxena S. Initial steps to developing the World Health Organization's Quality of Life Instrument (WHOQOL) module for international assessment in HIV/AIDS. AIDS Care 2010; 15(3): 347-57.
[12]
Eser E, Elbi H. Psychometric properties of the WHOQOL-100 and WHOQOL-BREF 1999. Available from: https://www.researchgate.net/publication/285059766
[13]
Ahmed A, Saqlain M, Akhtar N, et al. Translation and cross-cultural adaptation of WHOQOL-HIV Bref among people living with HIV/AIDS in Pakistan. Health Qual Life Outcomes 2021; 19(1): 48.
[http://dx.doi.org/10.1186/s12955-021-01693-0] [PMID: 33557861]
[14]
Quality of life assessment: International perspectives. Proceedings of the Joint-Meeting Organized by the World Health Organization and the Fondation IPSEN in Paris. July 2–3, 1993; 1994. 1994.
[15]
WHOQOL TRANSLATION METHODOLOGY. 2020. Available from: https://cdn.who.int/media/docs/default-source/publishing-policies/whoqol-100-guidelines/translation-methodology.pdf?sfvrsn=74cdb8f5_2
[16]
Guillemin F, Bombardier C, Beaton D. Cross-cultural adaptation of health-related quality of life measures: Literature review and proposed guidelines. J Clin Epidemiol 1993; 46(12): 1417-32.
[http://dx.doi.org/10.1016/0895-4356(93)90142-N] [PMID: 8263569]
[17]
Zhu Y, Liu J, Qu B. Psychometric properties of the Chinese version of the WHOQOL-HIV BREF to assess quality of life among people living with HIV/AIDS: A cross-sectional study. BMJ Open 2017; 7(8): e016382.
[http://dx.doi.org/10.1136/bmjopen-2017-016382] [PMID: 28827253]
[18]
Herdman M, Fox-Rushby J, Badia X. A model of equivalence in the cultural adaptation of HRQoL instruments: the universalist approach. Qual Life Res 1998; 7(4): 323-35.
[http://dx.doi.org/10.1023/A:1008846618880] [PMID: 9610216]
[19]
WHOQOL: Measuring Quality of Life.. Available from: https://www.who.int/tools/whoqol
[20]
R Core Team. The R Project for Statistical Computing. 2023. Available from: https://www.R-project.org
[21]
Posit team. RStudio: Integrated Development Environment for R. Boston, MA: Posit Software, PBC 2023.
[22]
Sjoberg DD, Whiting K, Curry M, Lavery JA, Larmarange J. Reproducible summary tables with the gtsummary package. R J 2021; 13(1): 570-80.
[http://dx.doi.org/10.32614/RJ-2021-053]
[23]
Wickham H, Averick M, Bryan J, et al. Welcome to the tidyverse. J Open Source Softw 2019; 4(43): 1686.
[http://dx.doi.org/10.21105/joss.01686]
[24]
Revelle W. Psych: Procedures for psychological, psychometric, and personality research. 2023. Available from: https://CRAN.R-project.org/package=psych
[25]
Johnson PE. Regression Estimation and Presentation [R package rockchalk version 1.8.157]. 2022. Available from: https://CRAN.R-project.org/package=rockchalk
[26]
Rosseel Y. Lavaan: An R package for structural equation modeling. J Stat Softw 2012; 48(2): 48.
[http://dx.doi.org/10.18637/jss.v048.i02]
[27]
irr: Various Coefficients of Interrater Reliability and Agreement. Available from: https://cran.r-project.org/web/packages/irr/index.html
[28]
Lynn MR. Determination and quantification of content validity. Nurs Res 1986; 35(6): 382-6.
[http://dx.doi.org/10.1097/00006199-198611000-00017] [PMID: 3640358]
[29]
Mîndrilă D. Maximum Likelihood (ML) and diagonally weighted least squares (DWLS) estimation procedures: A comparison of estimation bias with ordinal and multivariate non-normal data. IJDS 2010; 1(1)
[30]
Hsiung PC, Fang CT, Wu CH, Sheng WH, Chen SC, Der Wang J. Validation of the WHOQOL-HIV BREF among HIV-infected patients in Taiwan. AIDS Care 2011; 23(8): 1035-42.
[http://dx.doi.org/10.1080/09540121.2010.543881]
[31]
Pereira M, Martins A, Alves S, Canavarro MC. Assessing quality of life in middle-aged and older adults with HIV: Psychometric testing of the WHOQOL-HIV-Bref. Qual Life Res 2014; 23(9): 2473-9.
[http://dx.doi.org/10.1007/s11136-014-0707-7] [PMID: 24791929]
[32]
Starace F, Cafaro L, Abrescia N, et al. Quality of life assessment in HIV-positive persons: Application and validation of the WHOQOL-HIV, Italian version. AIDS Care 2002; 14(3): 405-15.
[http://dx.doi.org/10.1080/09540120220123793a] [PMID: 12042086]
[33]
Reychler G, Caty G, Vincent A, Billo S, Yombi JC. Validation of the french version of the world health organization quality of life HIV instrument. PLoS One 2013; 8(9): e73180.
[http://dx.doi.org/10.1371/journal.pone.0073180] [PMID: 24019904]
[34]
Saddki N, Noor MM, Norbanee TH, et al. Validity and reliability of the Malay version of WHOQOL-HIV BREF in patients with HIV infection. AIDS Care 2009; 21(10): 1271-8.
[http://dx.doi.org/10.1080/09540120902803216] [PMID: 20024703]
[35]
Salehi M, Niroumand S, Erfanian M, Sajjadi R, Dadgarmoghaddam M. Validation of Persian version of WHOQOL-HIV BREF questionnaire in Islamic Republic of Iran. East Mediterr Health J 2016; 22(9): 647-53.
[http://dx.doi.org/10.26719/2016.22.9.647] [PMID: 27966765]
[36]
Tesfaye M, Olsen MF, Medhin G, Friis H, Hanlon C, Holm L. Adaptation and validation of the short version WHOQOL-HIV in Ethiopia. Int J Ment Health Syst 2016; 10(1): 29.
[http://dx.doi.org/10.1186/s13033-016-0062-x] [PMID: 27064377]
[37]
Canavarro MC, Pereira M, Simões MR, Pintassilgo AL. Quality of life assessment in HIV-infection: Validation of the European Portuguese version of WHOQOL-HIV. AIDS Care 2011; 23(2): 187-94.
[http://dx.doi.org/10.1080/09540121.2010.498870] [PMID: 21259131]
[38]
Eser E, Fidaner C, Eser S, Elbi H, Göker E. Whoqol-100 and psychometric characteristics of WHOQOL-bref. Available from: https://www.researchgate.net/profile/Erhan-Eser/publication/291870682_Whoqol-100_and_psychometric_characteristics_of_WHOQOL-bref/links/584817e808aeda696825d91e/Whoqol-100-and-psychometric-characteristics-of-WHOQOL-bref.pdf
[39]
Crane H, Lober W, Webster E, et al. Routine collection of patient-reported outcomes in an HIV clinic setting: the first 100 patients. Curr HIV Res 2007; 5(1): 109-18.
[http://dx.doi.org/10.2174/157016207779316369] [PMID: 17266562]