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Current Pharmaceutical Biotechnology

Author(s): Yu Zhang, Ramizu Bin Shaari*, Mohamad Arif Bin Awang Nawi, Akram Bin Hassan and Caiyun Cui

DOI: 10.2174/0113892010276692231220103636

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Pharmacological Action and Research Progress of Taraxasterol

Page: [1767 - 1777] Pages: 11

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Abstract

Primarily sourced from Asteraceae family herbs such as the Dandelion, Taraxasterol is a pentacyclic triterpenoid lauded for its extensive biological functionalities. Its therapeutic potency is demonstrated in various disease models, encompassing enteritis, arthritis, acute hepatic injury, and pneumonia. Scientific literature underscores its anti-inflammatory, antioxidant, and antineoplastic attributes. The primary aim of this study is to thoroughly explore the diseasemodulating mechanisms and effects of taraxasterol. We endeavor to provide an exhaustive review of the experimental subjects, intervention components, distinct action modalities, contributing factors, and protein pathway expressions associated with taraxasterol, systematically represented via diagrams and tables. Such a schematic representation encourages a continued academic dialogue concerning taraxasterol's pharmacological characteristics. This review is envisioned as a practical guide for the selection of experimental subjects and methodologies in prospective research. It is intended to further illuminate taraxasterol's pharmacodynamics, thereby offering theoretical and empirical justification for its clinical application.

Keywords: Taraxasterol, sterol, dandelion, anti-inflammatory, anti-oxidation, anti-tumor, pharmacological.

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