Preparation of benzimidazole derivatives have become the interest of many chemists because of the versatile therapeutic activity of benzimidazoles as antiulcer, antimicrobial, antiviral, anticancer, anti-inflammatory, analgesic and anthelmintic drugs. This review will describe the most recent research on benzimidazole synthesis.
Keywords: Benzimidazole, 2, 5-dimethyl benzimidazole, 2-subsitituted benzimidazole, o-Phenylene diamine, 5-methyl benzimidazole, 6-dimethylbenzimidazole.