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The Natural Products Journal

Author(s): Simran Dhiman, Bhawna Chopra*, Ashwani K Dhingra, Ajmer Singh Grewal, Priyanka Kriplani, Geeta Deswal, Rameshwar Dass and Kumar Guarve

DOI: 10.2174/0122103155260889230919065953

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Cultivating Bone Health: Exploring Medicinal Plants and Bioactive Compounds for Osteoporosis Treatment

Article ID: e091023221916 Pages: 32

  • * (Excluding Mailing and Handling)

Abstract

Background: Osteoporosis is a severe bone condition characterized by a bone mineral density (BMD) 2.5 standard deviations below peak bone mass. Osteoporosis will become a serious issue as the population ages. Traditional anti-osteoporotic medications are effective in both the prevention and treatment of Osteoporosis. However, they are linked to several adverse effects, enabling many women to seek alternative treatment with medicinal herbs. Chinese herbs, which are all-natural products, are thought to treat Osteoporosis primarily by improving bone quality.

Methods: A literature survey has been carried out to determine the real potential of medicinal plants and their bioactive constituents in treating Osteoporosis.

Results: Many medicinal plants can modulate bone metabolism and thus reduce bone loss. TCM formulations and their constituent plant remedies have a wealth of phytochemicals with significant promise for discovering novel antiosteoporotic medications. The active substances in TCM formulae can be established as potency medications in combination with antiosteoporotic benefits that may be superior to those of the individual compounds.

Conclusion: The primary goal of the review is to describe the potential of antiosteoporosis medicinal plants and some of their phytoconstituents, along with an overview of osteoporosis pathogenesis, clinical studies, and their patent studies.

Graphical Abstract

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