Current Women`s Health Reviews

Author(s): Mansoureh Refaei, Zahra Cheraghi, Farzaneh Soltani and Batoul Khodakarami*

DOI: 10.2174/1573404820666230731125500

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Risk Factors Associated with Cervical Cancer: A Matched Case-control Study

Article ID: e310723219291 Pages: 7

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Abstract

Background: One of the most effective ways to prevent cervical cancer is to identify the risk factors for the disease.

Objective: The purpose of this research was to determine the risk factors for cervical cancer in women in Iran.

Methods: This was a matched case-control study. 105 participants (35 patients with cervical cancer and 70 healthy women) were selected from the registered patients and women attending a women’s specialized hospital in Hamadan, Iran. One case was matched to 2 controls by age (±3 years). Demographic and clinical data were collected using a semi-structured questionnaire. Conditional multivariate logistic regression model and STATA 11 software were used for data analysis.

Results: The mean age of women in the case and control group were 58.02(12.32) and 58.11(12.25) years (p = 0.486), respectively. Patients had lower education levels (p = 0.037), lower economic status (p˂0.001), and lower spouse education levels (p = 0.009). The results showed OCP users were 8.79 times more likely to develop cervical cancer than women who do not use OCP (p = 0.007), and the probability of cervical cancer in women increased by 8.33 times (<0.001) with decreasing each level of socio-economic status.

Conclusion: The results of the present study showed low economic status, and a history of using oral contraceptive pills are risk factors for cervical cancer.

Keywords: Cervical cancer, risk factors, case-control study, hormonal contraceptive pills, economic status, women.