Abstract
Research Problem: Hypertension, either high blood pressure or pulmonary hypertension,
both affect the life of patients in many ways.
Research Questions: Does Pulmonary hypertension similar to high blood pressure?
Does it affect old age people or the neonatal age groups also?
What were the reasons for pulmonary hypertension?
Does pulmonary hypertension manageable with modern and traditional drugs?
Literature Review: The purpose of the literature review is to identify the targeted therapy for pulmonary
hypertension and also include the plants that may be effective for the management of pulmonary
hypertension.
Conclusion: The author has reviewed many targeted drugs that are presently used, and many are in
research that was found effective in making the life of patients as normal as possible.
They also reviewed about 15 herbal plants which were found effective in the management of the
disease.
As pulmonary hypertension is not treatable, it can only be managed by changing lifestyle and food
habits; therefore, the authors emphasized reviewing the traditional approach for the management of
pulmonary hypertension.
Graphical Abstract
[10]
Woodard TJ, Kim C, Siao FA. Review of the diagnosis and management of pulmonary arterial hypertension. US Pharm 2018; 43(3): HS10-6.
[37]
Channick RN, Voswinckel R, Rubin LJ. Inhaled treprostinil: A therapeutic review. Drug Des Devel Ther 2012; 6: 19-28.
[48]
Tung NH, Hung LQ, Van Oanh H, et al. Bioactive phenolic compounds from the roots of danshen (Salvia miltiorrhiza). Natural Product Communications 2018; 13(10): 1305-7.
[53]
Kashif M, Ullah S. Chemical composition and minerals analysis of Hippophaerhamnoides, Azadirachta indica, Punica granatum and Ocimum sanctum leaves. World J Dairy Food Sci 2013; 8(1): 67-73.
[55]
Lei XL, Chiou GC. Cardiovascular pharmacology of Panax notoginseng (Burk) F.H. Chen and Salvia miltiorrhiza. Am J Chin Med 1986; 14(3-4): 145-52.
[58]
Rout SK, Dutta S, Sengupta M, Das S, Rout B. Antihypertensive therapy: The concepts of management with herbal and synthetic agents for pulmonary hypertension. Int J Pharm Sci Rev Res 2010; 3(2)
[59]
Ahmadipour B, Kalantar M, Hosseini SM. Hawthorn (Crataegus oxyacantha) Flavonoid extract as an effective medicinal plant derivative to prevent pulmonary hypertension and heart failure in broiler chickens. Kafkas Univ Vet Fak Derg 2019; 25(3): 321-8.
[66]
Chiang HM, Chen HC, Wu CS, Wu PY, Wen KC. Rhodiola plants: Chemistry and biological activity. J Food Drug Anal 2015; 23(3): 359-69.
[69]
Venkitasamy C, Zhao L, Zhang R, Pan Z. Integrated processing technologies for food and agricultural by-products. Amsterdam: Elsevier 2019; pp. 181-216.
[71]
Nik AB, Vazifedoost M, Didar Z, Hajirostamloo B. The antioxidant and physicochemical properties of microencapsulated bioactive compounds in Securigera securidaca (L) seed extract by co-crystallization Food Quality and Safety. Oxford: Academic 2019; p. 25.
[76]
Singh B, Hathan BS. Chemical composition, functional properties and processing of beetroot-a review. Int J Sci Eng Res 2014; 5(1): 679-84.
[81]
Lisa J. Biotechnology of Fruit and Nut Crops (Biotechnology in Agriculture Series). Washington. Amazon 2020; 29: 703.
[84]
Wu X, Kang J. Blueberries: Major phytochemicals and potential health effects in cardiovascular diseasesBerries: Properties, Consumption and Nutrition. New York, NY, USA: Nova Biomedical Books 2012; pp. 83-104.
[85]
Howard L, Hagar T. Berry fruit phytochemicalsBerry Fruit: Value Added Products for Health Promotion. Boca Raton, FL, USA: CRC Press 2007; pp. 73-105.
[90]
Dermarderosian A, Beutler JA. Review of natural products: The most complete source of natural product information. Philadelphia: Lippincott Williams & Wilkins 2001.