Abstract
Dementia is a brain disorder with progressive neurological disease. It destroys essential
brain cells, impairing memory, thinking, and behavior in a severe way to impact health, enduring
interests, and social life. Memory, cognition, orientation, learning capacity, language, and judgments
gradually get impaired. Dementia results from anatomical and functional abnormalities, cerebral
ischemia, energy deficits, calcium excess, glutamate-mediated excitotoxicity, and oxidative
stress. Vascular dementia (VaD), which accounts for 10-15% of dementia cases, is the second most
frequent form of dementia after Alzheimer's disease (AD). There are currently no approved pharmaceutical
treatments for VaD, and traditional anti-AD therapies only offer modest, temporary relief
from the symptoms of VaD. Since herbal remedies have a multicomponent and multitarget approach,
they may provide effective treatments for VaD. Herbal remedies have been used for centuries
to address dementia-like symptoms. This author describes some preliminary research that supports
using herbal drugs in managing vascular dementia and dementia.
Keywords:
Dementia, curcuma longa, vascular dementia, memory, cognition, Alzheimer’s diseases.
Graphical Abstract
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