Abstract

microRNAs (miRNA) play a significant role in regulating gene expression at the posttranscriptional level in multicellular organisms, such as mammals. These small non-coding RNAs (snRNA) can be present in plants and even viruses, and make up about 60% of human genes. Many different functions and roles are played by miRNAs, including their role in many diseases and cancers. The results of various studies in recent years on the role of miRNA-337 in cancers have shown that miR-337 acts as a cancer inhibitor and can play a key role in the treatment of various cancers by inhibiting cell invasion. Thus, among the various miRNAs, in this review, we aim to shed light on the function of miR-337 in different types of cancer.

Keywords: Cancer, miRNA, ssRNA, hepatocellular carcinoma, circRNA, proto-oncogenes.