Abstract
This patent describes the synthesis of compounds, methods, and compositions
for preventing, treating, and/or curing Covid-19, human coronavirus, and enterovirus infections.
Some peptidomimetic compounds are very potent and could be a game changer
in new treatment therapy for COVID-19.
Keywords:
COVID-19, human coronavirus, enterovirus, peptidomimetic, paxlovid, therapy for COVID-19.
[21]
Owen, D.R.; Allerton, C.M.N.; Anderson, A.S.; Aschenbrenner, L.; Avery, M.; Berritt, S.; Boras, B.; Cardin, R.D.; Carlo, A.; Coffman, K.J.; Dantonio, A.; Di, L.; Eng, H.; Ferre, R.; Gajiwala, K.S.; Gibson, S.A.; Greasley, S.E.; Hurst, B.L.; Kadar, E.P.; Kalgutkar, A.S.; Lee, J.C.; Lee, J.; Liu, W.; Mason, S.W.; Noell, S.; Novak, J.J.; Obach, R.S.; Ogilvie, K.; Patel, N.C.; Pettersson, M.; Rai, D.K.; Reese, M.R.; Sammons, M.F.; Sathish, J.G.; Singh, R.S.P.; Steppan, C.M.; Stewart, A.E.; Tuttle, J.B.; Updyke, L.; Verhoest, P.R.; Wei, L.; Yang, Q.; Zhu, Y. An oral SARS-CoV-2 M pro inhibitor clinical candidate for the treatment of COVID-19.
Science, 2021,
374(6575), 1586-1593.
[
http://dx.doi.org/10.1126/science.abl4784] [PMID:
34726479]