The Future is Now for Precision Genomic Addiction Medicine as a Frontline
Modality for Inducing “Dopamine Homeostasis” in Reward Deficiency
Syndrome (RDS)

Elizabeth   D.   Gilley; Abdalla      Bowirrat; Ashim      Gupta; John      Giordano; Catherine   A.   Dennen; Eric      Braverman; Rajendra   D.   Badgaiyan; Thomas      McLaughlin; David      Baron; Kenneth      Blum
Abstract

In this genomic era of addiction medicine, ideal treatment planning begins with genetic screening to determine neurogenetic antecedents of the Reward Deficiency Syndrome (RDS) phenotype. Patients suffering from endotype addictions, both substance and behavioral, and other mental health/comorbid disorders that share the neurobiological commonality of dopamine dysfunction, are ideal candidates for RDS solutions that facilitate dopamine homeostasis, addressing the cause, rather than symptoms. Our goal is to promote the interplay of molecular biology and recovery as well as provide evidence linked to RDS and its scientific basis to primary care physicians and others. This was an observational case study with a retrospective chart review in which an RDS treatment plan that utilized Genetic Addiction Risk Severity (GARS) analysis to evaluate neurogenetic challenges was used in order to develop appropriate short- and long-term pharmaceutical and nutraceutical interventions. A Substance Use Disorder (SUD) treatment-resistant patient was successfully treated utilizing the GARS test and RDS science. The RDS Solution Focused Brief Therapy (RDS-SFBT) and the RDS Severity of Symptoms Scale (SOS) may provide clinicians with a useful tool for establishing neurological balance and helping patients to achieve selfefficacy, self-actualization, and prosperity.
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Cite As
Current Pharmaceutical Biotechnology

The Future is Now for Precision Genomic Addiction Medicine as a Frontline Modality for Inducing “Dopamine Homeostasis” in Reward Deficiency Syndrome (RDS)

Abstract
