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Current Pharmaceutical Biotechnology

Author(s): Holger Thie, Torsten Meyer, Thomas Schirrmann, Michael Hust and Stefan Dubel

DOI: 10.2174/138920108786786349

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Phage Display Derived Therapeutic Antibodies

Page: [439 - 446] Pages: 8

  • * (Excluding Mailing and Handling)

Abstract

This article gives an overview about the development of human therapeutic antibodies generated by phage display. After an introduction to the method, the focus is on approved antibodies and those currently in clinical trials, 14 of which are described in detail.

Keywords: Therapeutic Antibodies, phage display, clinical trials, CHO producer cells, immune system, GENE LIBRARIES