Current Organic Synthesis

Author(s): Priyanuj Krishnann Hazarika, Roktopol Hazarika and Diganta Sarma*

DOI: 10.2174/1570179420666230322155524

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Recent Advances in Metal Free Synthesis of N-unsubstituted 1,2,3-Triazoles

Page: [10 - 19] Pages: 10

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Abstract

1, 2, 3-triazoles display enormous applications in the extensive fields of chemistry such as pharmaceuticals, ligands, conjectures, etc. Among these classes of compounds, the Nunsubstituted triazole emerges as a potent applicant for various fields of chemistry and therefore synthetic procedures for this molecular scaffold possess certain importance. Moreover, from an environmental perspective, metal-free organic synthesis gains tremendous attention as most of the metals are persistent in nature. In this review, we are going to discuss only the metal-free synthetic routes for the construction of N-unsubstituted 1,2,3-triazoles reported during the last decade.

Keywords: 1, 2, 3-triazoles, N-unsubstituted 1, 2, 3-triazoles, NH-triazoles, metal free synthesis, green synthesis, scaffold.

Graphical Abstract