Current Organic Synthesis

Author(s): Surya K. De*

DOI: 10.2174/1570179420666230320120852

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Recent Discovery of Triazine Derivatives as Protease Inhibitors for the Treatment of Coronavirus-19 (COVID-19)

Page: [91 - 95] Pages: 5

  • * (Excluding Mailing and Handling)

Abstract

The present application describes a class of compounds exhibiting a coronavirus 3CL protease inhibitory effect and pharmaceutically acceptable salts thereof, and a pharmaceutical composition containing the same. The application also provides the synthesis of compounds and efficacy from in vitro and cell- based assays.

Keywords: Coronavirus-19, paxlovid, protease inhibitor, triazine derivatives, nidovirales, synthesis.