Protein & Peptide Letters

Author(s): Andre N ewton Monte Negreiros, Artur Torres Cordeiro and Carlos Bloch Jr.*

DOI: 10.2174/092986650701221205150204

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Amino acid sequence and molecular modeling of a lipid transfer protein from the seeds of prosopis juliflora and its interaction with palmitic acid

Page: [17 - 24] Pages: 8

  • * (Excluding Mailing and Handling)

Abstract

A basic, ninety two amino acid residue polypeptide, called CM4-3, was purified from seeds of Prosopis juliflora and sequenced. Sequence homology searches indicated that this protein is related to the nonspecific lipid transfer protein family (ns-LTP). A 3D model of CM4-3 was built base on the molecular coordinates of a maize ns-LTP and the obtained model revealed the presence of a highly conserved pocket formed by three a-helices capable of accommodating one molecule ofpalrnitic acid inside the CM4-3 structure.