The heightened attention to food and health safety has prompted researchers to conduct extensive research on biosensors that quickly detect foodborne microbial toxins and pathogens. Biosensors are a blessing due to their simple, cost-effective technique, but there are still some drawbacks with detection time, detection limit, and resilience. Incorporating functionalized nanomaterials into developing biosensors as catalytic tools, immobilization platforms, or optical or electroactive labels has added a new dimension to addressing these challenges. This review paper aims to discuss the construction of different types of nanomaterial-based biosensors in food safety, exosome detection and finally, cancer detection, as well as highlights the advantages of these biosensors over traditional techniques. In addition, a comparative study between the nanomaterial-based biosensors taking into account the linear range and limits of detection in these mentioned applications was also conducted. Hence, this paper provides key insights into designing and fabricating biosensors utilizing nanomaterials and opens new avenues in disease and food safety research.
Keywords: Electrochemical biosensor, colorimetric biosensors, fluorescent biosensors, nanomaterial, nanocomposite