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Current Nanoscience

Author(s): Mahendra Rai*, Avinash P. Ingle, Alka Yadav, Patrycja Golińska, Joanna Trzcińska-Wencel, Sanjay Rathod and Shital Bonde

DOI: 10.2174/1573413718666220426101432

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Nanotechnology as a Promising Approach for Detection, Diagnosis and Treatment of Food Allergens

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Abstract

Food allergy is one of the world's most serious health problems, which needs new and safer approaches to resolve it. The rapid progress of nanotechnology to tackle the problem of food allergen has generated a new hope. Nanoparticles can be used as a unique system to detect allergens. Furthermore, nanotechnology offers allergen-delivery systems based on nanoparticles as potential adjuvants for allergen-specific immunotherapy. In addition, the use of novel adjuvants using nanoparticles provides a harmless and potentially more effective way of treatment for allergic diseases. For therapeutic applications, nanotechnology-based delivery systems provide increased bioavailability and targeted delivery of food allergens. In addition, nano-based allergen-delivery approaches are mainly aimed at devising a novel and promising approach for allergy vaccines. This review discusses the potential role of nanotechnological strategies for detection, drug delivery, and the treatment of allergies.

Keywords: Food allergens, nanoparticles, diagnosis, delivery, treatment, immunotherapy.

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