Abstract
Background: Diabetes mellitus is a chronic metabolic disorder, the prevalence of which
is increasing alarmingly throughout the world and imposes a serious impact on the health of the
population as well as national economies. Effective management and primary prevention are essential
to decrease the burden of diabetes faced by all nations. Although different therapies are available
for diabetes, no known therapy can completely cure the disease, and many of them have a number
of side effects with other limitations like long-term treatment, expensiveness, and less availability.
Hence, the present review has given an emphasis on common dietary materials to find out a
readily available source of anti-diabetic agents.
Objective: The purpose of this work is to explore the anti-diabetic properties of certain spices which
are most frequently used in Bangladesh and reported for their use in traditional treatment of diabetes
and/or investigated scientifically for anti-diabetic activity.
Methods: Two electronic databases, namely Pub Med and Google Scholar, were used for conducting
a comprehensive search to collect information and data.
Results: In this review, a total of 10 spices have been compiled with a brief description of their
origin, part used, chemical constituents, mechanism of action, methods of experiment, model animals,
and reported beneficial effects in diabetes with other pharmacological activities.
Conclusion: The observed results of this study indicate the possibility of developing a therapeutic
strategy called alternative and complementary medicine for the management of diabetes. The results
also provide a starting point for researchers working with bioactive dietary plants with anti-diabetic
potential.
Keywords:
Diabetes mellitus, anti-diabetic potentials, pharmacological activities, traditional medicine, spices, diet.
Graphical Abstract
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