Abstract
Background: COVID-19 is still soaring, and the new delta COVID-19 variant is
on the rise and spreading around the world.
Objective: We conducted a patent analysis to better understand the therapeutic strategy developed
for antivirals available for the disorders of the respiratory system.
Materials and Methods: European granted patents filed from January 2002 to June 2021
were analyzed. We used a combination of International patent classification (IPC)
“A61p31/12” and “A61p11/00” to search the relevant documents.
Results: Our study showed R&D of antiviral drugs for disorders of the respiratory system to
be decreasing over the past 20 years. Chemical drugs showed various chemical structures.
The development of chemical drugs or herbal medicines appeared to commence earlier than
the biological products. Also, the results indicated that large global companies play a leading
role in developing kinase inhibitors as chemical drugs.
Conclusion: There are three strategies for developing antiviral drugs for the disorders of the
respiratory system, including chemical drugs, herbal medicines or natural products, and biological
products. Herbal medicines may provide a new insight and approach to developing
antiviral drugs for disorders of the respiratory system. A combination of chemical drugs and
natural products may be a promising therapeutic method for treating patients with COVID-
19.
Keywords:
Antiviral drugs, patent, therapeutic strategy, COVID-19, kinase inhibitors, herbal medicines.
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