Digitization of Prior Authorization in Healthcare Management Using Machine Learning

Article ID: e120422203460 Pages: 11

  • * (Excluding Mailing and Handling)

Abstract

Background: Prior Authorization is a widely used process by health insurance companies in the United States before they agree to cover prescribed medication under medical insurance. However, the traditional approach includes long-length papers, leading to patients' delayed processing of their claims. This delay may deteriorate the patient’s medical condition. Also, due to man-made errors, there is a chance of incorrect decision-making on the claims. On the other hand, physicians are losing their time getting their prescribed medication approved. It is essential to reduce the wait time of patients and the tedious work of physicians for healthcare to be effective. This demands advanced technology that can boost the decision-making process of prior authorization methodology.

Objective: This work aims to digitize the prior authorization process by implementing classification algorithms to classify the initial authorization applications into Accepted/Rejected/Partially Accepted classes. A web application that inputs prior authorization claim details and outputs the predicted class of the claim was proposed.

Methods: Analyzed and collected significant features by implementing feature selection. Developed classification models using Artificial Neural Networks and Random Forest. Implemented model validation techniques to evaluate classifier performance.

Results: From the research findings, generic medication cost, type of health insurance plan, addictive nature and side effects of the prescribed drug, patient physical qualities like Age/Gender/Current Medical condition are the significant attributes that impact the decisionmaking process in the prior authorization process. Then, implemented classifiers exhibited accurate performance on the Train and Test data. Amongst Artificial Neural Networks classification model portrayed higher accuracy. Further a confusion matrix was further analyzed for developed models. In addition, k-fold cross-validation and availed performance evaluation metrics were conducted to validate the model performance.

Conclusion: Ameliorated Healthcare by removing time and location barriers in the Prior Authorization process while ensuring patients get quality and economical medication. The proposed web application with a machine learning predictive model as a backend automates the prior authorization process by classifying the applications in a few seconds.

Keywords: Prior authorization, machine learning, classification, digitization, healthcare, health insurance, economical medica-tion.

Graphical Abstract

[1]
Morris L. Combating fraud in health care: an essential component of any cost containment strategy. Health Aff (Millwood) 2009; 28(5): 1351-6.
[http://dx.doi.org/10.1377/hlthaff.28.5.1351] [PMID: 19738251]
[2]
Cohen AM, Hersh WR, Peterson K, Yen P-Y. Reducing workload in systematic review preparation using automated citation classification. J Am Med Inform Assoc 2006; 13(2): 206-19.
[http://dx.doi.org/10.1197/jamia.M1929] [PMID: 16357352]
[3]
Magalhães VG Jr, Vieira AJP, Lira de Sales Santos R, Nascimento Barbosa JL, de Alcântara dos Santos Neto P, Santos Moura R. A study of the influence of textual features in learning medical prior authorization. IEEE 32nd International Symposium on ComputerBased Medical Systems (CBMS). 2019 June 5-7; Cordoba, Spain. IEEE Xplore. 2019.
[http://dx.doi.org/10.1109/CBMS.2019.00021]
[4]
Sarafidis M, Tarousi M, Anastasiou A, et al. Data quality challenges in a learning health system. Stud Health Technol Inform 2020; 270: 143-7.
[PMID: 32570363]
[5]
Verma AK, Pal S, Kumar S. Prediction of skin disease using ensemble data mining techniques and feature selection method-a comparative study. Appl Biochem Biotechnol 2020; 190(2): 341-59.
[http://dx.doi.org/10.1007/s12010-019-03093-z] [PMID: 31350666]
[6]
Hillerman TP, Carvalho RN, Reis ACB. Analyzingsuspicious medical visit claims from individual healthcare service providers using K-Means clustering. In: electronic government and the information systems perspective. 2015 Sep 1- 3; Valencia, Spain. Springer Lecture Notes in Computer science. 2015.
[7]
Guido van Rossum. Python: “Python Software Foundation version 37,”. 2019. Available from: https://www.python.org/downloads/
[8]
Birdsall AD, Kappenman AM, Covey BT, Rim MH. Implementation and impact assessment of integrated electronic prior authorization in an academic health system. J Am Pharm Assoc (Wash DC) 2020; 60(4): e93-9.
[http://dx.doi.org/10.1016/j.japh.2020.01.012] [PMID: 32107157]
[9]
Donna Marbury. Electronic prior authorization is catching on. MHE Publication 2020.
[10]
Forrester C. Benefits of prior authorizations. J Manag Care Spec Pharm 2020; 26(7): 820-2.
[http://dx.doi.org/10.18553/jmcp.2020.26.7.820] [PMID: 32584679]
[11]
Centers for Medicare and Medicad Services. Official website of the United States Governement. 2021. Available from: https://www.cms. gov/research-statistics-data-systems/medicare-fee-service-compliance-programs/prior-authorization-and-pre-claim-review-initiatives
[12]
Oklahoma Health Care Authority- Prior Authorization Unit. 2020. Available from: https://oklahoma.gov/ohca/providers/claim-tools/prior-authorization.html
[13]
Centers for Disease Control and Prevention. 2018. Available from: https://www.cdc.gov/phlp/publications/topic/hipaa.html
[14]
Data Set Reference Link. 2021. Available from: https://github.com/sahithi84/Prio_Authorization/
[15]
Tabassum S, Sampa MB, Islam R. A Data Enhancement Approach to Improve Machine Learning Performance for Predicting Health Status Using Remote Healthcare Data. 2nd International Conference on Advanced Information and Communication Technology (ICAICT). 28-29 November 2020; Dhaka, Bangladesh. 2020.
[http://dx.doi.org/10.1109/ICAICT51780.2020.9333506]
[16]
Jackson E, Agrawal R. Performance evaluation of different feature encoding schemes on cybersecurity logs 11-14 April 2019. Huntsville, USA. 2019;
[http://dx.doi.org/10.1109/SoutheastCon42311.2019.9020560]
[17]
Mitchell MT, McGraw H. Machine Learning, 1st Ed. a standard reference textbook for Machine Learning. 1996; pp. 5-12.
[18]
Li H, Pi D, Wu Y, Chen C. Integrative method based on linear regression for the prediction of zinc binding sites in proteins. IEEE Access 2017; 5: 14647-56.
[http://dx.doi.org/10.1109/ACCESS.2017.2731872]
[19]
Acosta MRC, Ahmed S, Garcia CE, et al. Extremely randomized trees-based scheme for stealthy cyber-attack detection in smart grid net-works. IEEE Access 2020; 8: 19921-33.
[http://dx.doi.org/10.1109/ACCESS.2020.2968934]
[20]
Farias K, Neto PS, Santana A, Neto RB. Using historical information of patients for prior authorization learning. 8th Brazilian Conference on Intelligent Systems (BRACIS). 2019; pp. 598-603.
[http://dx.doi.org/10.1109/BRACIS.2019.00110]
[21]
Ahn E, Kumar A, Feng D, Fulham M, Kim J. Unsupervised feature learning with K-means and an ensemble of deep convolutional neural networks for medical image classification Arvix 2019. https://arxiv.org/abs/1906.03359
[22]
Jain V, Kulkarni A. Survey on various algorithms of machine learning and its applications. Int Res J Eng Technol 2020; 7(10): 794-8.
[23]
Kazhdan D, Shams Z, Liò P. Marlene: A multi-agent reinforcement learning model extraction library. Arvix 2020. https://arxiv.org/abs/2004.07928
[24]
de Araujo FHD, Santana AM, de Alcantara dos Santos Neto P. Evaluation of classifiers based on decision tree for learning medical claim process. Rev IEEE Am Lat 2015; 13(1): 299-306.
[http://dx.doi.org/10.1109/TLA.2015.7040662]
[25]
Wang S, Wang Y, Wang D, Yin Y, Wang Y, Jin Y. An improved random forest-based rule extraction method for breast cancer diagnosis. Appl Soft Comput 2020; 10594: 105941.
[http://dx.doi.org/10.1016/j.asoc.2019.105941]
[26]
Masetic Z, Subasi A. Congestive heart failure detection using random forest classifier. Comput Methods Programs Biomed 2016; 130: 54-64.
[http://dx.doi.org/10.1016/j.cmpb.2016.03.020] [PMID: 27208521]
[27]
Li J, Tian Y, Zhu Y, et al. A multicenter random forest model for effective prognosis prediction in collaborative clinical research network. Artif Intell Med 2020; 103: 101814.
[http://dx.doi.org/10.1016/j.artmed.2020.101814] [PMID: 32143809]
[28]
Hammou BA, Lahcen AA, Mouline S. An effective distributed predictive model with Matrix factorization and random forest for Big Data recommendation systems. Expert Syst Appl 2019; 137.
[29]
Singh H, Lone YA. Artificial neural networks. In: Deep NeuroFuzzy Systems with Python Berkeley, CA: A press. 2020; pp. 157-98.
[http://dx.doi.org/10.1007/978-1-4842-5361-8_5]
[30]
Cassimiro JC, Andre S, Neto PS, Rabelo RL. Investigating the Effects of Class Imbalance in Learning the Claim Authorization Process in the Brazilian Health Care Market Conference on Neural Networks (IJCNN). 14-19 May 2017; Anchorage, USA. 2017.
[http://dx.doi.org/10.1109/IJCNN.2017.7966265]
[31]
Bandyopadhyay S, Thakur SS. Product prediction and recommendation in e-commerce using collaborative filtering and artificial neural networks: A hybrid approach Intelligent Computing Paradigm: Recent Trends. Springer 2020; pp. 59-67.
[http://dx.doi.org/10.1007/978-981-13-7334-3_5]
[32]
Singhal P, Pareek S. Artificial neural network for prediction of breast cancer. 2nd International Conference on I-SMAC (IoT in Social, Mobile, Analytics, and Cloud)(I-SMAC). 2018; 464-8.
[http://dx.doi.org/10.1109/I-SMAC.2018.8653700]
[33]
Khan NM, Abraham A, Hon M. Transfer learning with intelligent training data selection for prediction of Alzheimer’s disease. IEEE Access 2019; 7: 72726-35.
[34]
Araújo FH, Santana AM. de A Santos Neto P. Using machine learning to support healthcare professionals in making preauthorisation deci-sions. Int J Med Inform 2016; 94: 1-7.
[http://dx.doi.org/10.1016/j.ijmedinf.2016.06.007] [PMID: 27573306]
[35]
Hong WS, Haimovich AD, Taylor RA. Predicting hospital admission at emergency department triage using machine learning. PLoS One 2018; 13(7): e0201016.
[http://dx.doi.org/10.1371/journal.pone.0201016] [PMID: 30028888]
[36]
Okimoto LC, Savii RM, Lorena AC. Complexity measures effectiveness in feature selection.Brazilian Conference on Intelligent Systems (BRACIS) 2017; 91-6.
[http://dx.doi.org/10.1109/BRACIS.2017.66]
[37]
Gupta TK, Raza K. Optimization of ANN architecture: a review on nature-inspired techniques. In: machine learning in bio-signal analysis and diagnostic imaging. Academic Press 2019; 1: pp. 159-82.
[http://dx.doi.org/10.1016/B978-0-12-816086-2.00007-2]