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Current Medical Imaging

Author(s): Lili Yang, Jiawei He, Xiaoji Lin, Dandan Zhao, Xianhui Lin, Zhihan Yan* and Feng Chen*

DOI: 10.2174/1573405618666220329210311

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B-Cell Lymphoma Associated with COVID‐19 Infection: A Case Report

Article ID: e290322202796 Pages: 4

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Abstract

Purpose: Most common publications are related to COVID-19 diagnosis in hematological malignancy patients. However, here we report a case involving a patient diagnosed with B-cell lymphoma while undergoing treatment for COVID‐19, including the changes in major clinical symptoms and medical examinations, then explain the probable causes of the case.

Case Presentation: A 74-year-old woman with a previous history of oesophageal cancer was admitted to the hospital after having cough and sputum for 15 days. Despite the COVID-19 symptoms, this patient did not have a fever at the time of the onset. Results of routine blood tests were normal at first but then declined with persistent fever, and A whole-body C.T. examination ruled out the possibility of tumor-metastasis–related fever. This patient had no hepatosplenomegaly or regional lymphadenopathy, and there was no concrete evidence of haemophagocytic lymphohistiocytosis or lymphoma until bone marrow biopsy results confirmed the latter.

Conclusion: We describe an uncommon case of COVID-19 who was finally diagnosed with B-cell lymphoma. An awareness of persistent fever and declined routine blood tests caused by hematological malignancies instead of COVID-19 itself can aid in providing appropriate guidelines for management and treatment.

Keywords: COVID-19, SARS-CoV-2, lymphomas, fever, infection, malignancy.

Graphical Abstract

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