Abstract
Background and Objectives: Diabetes Mellitus, commonly known as DM, is a metabolic
disorder which is characterized by high blood glucose level, i.e., chronic hyperglycemia. If it is not
managed properly, DM can lead to many severe complexities with time and can cause significant damage
to the kidneys, heart, eyes, nerves and blood vessels. Diabetic foot ulcers (DFU) are one of
those major complexities which affect around 15-25% of the population diagnosed with diabetes.
Due to diabetic conditions, the body's natural healing process slows down leading to longer duration
for healing of wounds only when taken care of properly. Herbal therapies are one of the approaches
for the management and care of diabetic foot ulcer, which utilizes the concept of synergism for better
treatment options. With the recent advancement in the field of nanotechnology and natural drug
therapy, a lot of opportunities can be seen in combining both technologies and moving towards a more
advanced drug delivery system to overcome the limitations of polyherbal formulations.
Methods: During the writing of this document, the data was derived from existing original research
papers gathered from a variety of sources such as PubMed, ScienceDirect, Google Scholar.
Conclusion: Hence, this review includes evidence about the current practices and future possibilities of
nano-herbal formulation in treatment and management of diabetic wounds.
Keywords:
Diabetes Mellitus (DM), diabetic wound, chronic wound, wound healing, polyherbal nano formulation, nanotechnology.
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