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Reviews on Recent Clinical Trials

Author(s): Evanthia Letsiou, Sergios Tsakatikas, George Vakis, Konstantinos Tsapakidis, Nikolaos Charalampakis, Alexandros Diamantis, Antigoni Poultsidi, Dimosthenis Michelakis, Eelco de Bree, Davide Mauri, Nikolaos Tsoukalas, Chrysostomos Antoniades and Maria Tolia*

DOI: 10.2174/1574887117666220314161609

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Radiotherapy and Breast Reconstruction: What Is the Ideal Timing? A Narrative Review

Page: [73 - 85] Pages: 13

  • * (Excluding Mailing and Handling)

Abstract

Introduction: Women undergoing mastectomy choose to pursue breast reconstruction (BR) in order to reduce their body image distress.Adjuvant chest wall irradiation is associated with a negative cosmetic outcome. The aim of our review was to identify the optimal timing of BR relating to radiotherapy delivery.

Materials and Methods: Using Cochrane Library, Embase, PubMed, Springer, Wanfang and CNKI, we performed a non-systematic review of articles published up to August 2021.

Results: There is no hard evidence in favor of immediate, delayed or 2-stage BR when post-mastectomy radiation is indicated. Immediate and 2-stage BR seem to be valid alternatives to delayed BR.

Conclusions: Further research is essential in order to assess clinician and patient reported aesthetic outcomes and determine the optimal timing of BR in view of post-mastectomy radiotherapy, in breast cancer survivors.

Keywords: Breast, cancer, breast reconstruction, radiotherapy, timing, review.

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