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The Natural Products Journal

Author(s): Fernanda Manhães Braga Gonçalves*, Adriana Lima de Sousa, Marcelo da Silva Mathias, Jéssica da Silva Maciel and Rodrigo Rodrigues de Oliveira

DOI: 10.2174/2210315512666220303153835

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Phytochemical and Chemotaxonomic Investigations on Coussapoa Microcarpa (Cecropieae, Urticaceae)

Article ID: e030322201666 Pages: 8

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Abstract

Background: The Coussapoa genus (Urticaceae, tribe Cecropieae) contains 50 species mainly distributed throughout the Neotropical region. Although some genera belonging to the Cecropieae tribe have been well-assessed, the chemical profile of Coussapoa members has not yet been investigated.

Objective: In this context, the aim of the present study was to characterize phenolic substances present in a methanol extract obtained from Coussapoa microcarpa leaves employing UPLC-DAD-ESI-MS analyses.

Methods: Several condensed tannins (epi-afzelechin-epi-catechin, B-type and C-type procyanidins), flavan-3-ols ((+) -catechin and (-) - epicatechin), phenolic acid (O-caffeoylquinic acid) and C-glycosyl flavones (orientin, isoorientin, vitexin, isovitexin, isoorientin-2″-O-rhamnoside, vitexin-2″-Ohexoside, vitexin-2″-O-xyloside and isovitexin-2″-O-xyloside) were identified.

Results: The determined chemical profile observed for C. microcarpa exhibits chemo-taxonomic significance compared to other neotropical genera.

Conclusion: Structural variability of the identified secondary metabolites is of significant value for chemosystematic studies concerning the Coussapoa genus and the Cecropieae tribe, both still unexplored with respect to their chemodiversity.

Keywords: Urticaceae, Cecropieae, Coussapoa, Coussapoa microcarpa, flavonoids, UPLC-DAD-ESI-MS.

Graphical Abstract

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