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Infectious Disorders - Drug Targets

Author(s): Saumya Srivastava, Aditya Kundu, Haripriya Sivakumar, Vibhor Tak*, Durga Shankar Meena, Subhashree Samantray and Deepak Kumar

DOI: 10.2174/1871526522666220218114426

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A Case of Toxoplasma gondii and Strongyloides stercoralis Coinfection in an Immunocompromised Patient

Article ID: e180222201280 Pages: 3

  • * (Excluding Mailing and Handling)

Abstract

Background: In India, around 23.49 lac people have HIV/AIDS (PLHA). Strongyloidiasis and toxoplasmosis are some of the opportunistic infections that occur in HIV patients, but their dual coinfection with HIV is rarely reported.

Case Presentation: A 46-year-old male was admitted to the hospital with generalized weakness, loss of weight, and bleeding per rectum for the last 3 months and a few episodes of dizziness and fever.

Results: On routine investigation, he was diagnosed with human immunodeficiency virus (HIV) infection. On further evaluation, Toxoplasma gondii and Strongyloides stercoralis coinfection, as assessed by the parasitological diagnosis of the serum sample, was positive. Patient was started on artesunate, ART regimen (Tab, TLD- Dolutegravir 50 + Lamivudine 300 + Tenofovir DF 300) and cotrimoxazole.

Conclusion: Herein, we report a case of Toxoplasma gondii and Strongyloides stercoralis coinfection in an immunocompromised patient.

Keywords: Toxoplasma gondii, Strongyloides stercoralis, HIV, immunosuppression, coinfection, PLHA.

Graphical Abstract

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