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Current Organic Chemistry

Author(s): Mohammad A. Alam*

DOI: 10.2174/1385272826666220214110118

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Domino/Cascade and Multicomponent Reactions for the Synthesis of Thiazole Derivatives

Page: [343 - 347] Pages: 5

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Abstract

Substituted thiazoles are widely known as natural products, approved drugs, and a number of synthetic compounds as bioactive agents. Due to the worth of this heterocycle nucleus, a large number of synthetic methodologies have been reported over the years to synthesize its derivatives. In this perspective, recent advances in the synthesis of thiazole compounds by using domino/cascade and multicomponent approaches have been summarized.

Keywords: Domino/cascade reaction, multicomponent reaction, thiazole, thiazoline, fused-thiazole, anticancer, thiazolo-androstenone, isothiazole.

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