A New Insight into the Synthesis and Biological Activities of Pyrazole
based Derivatives

Satbir      Mor; Mohini      Khatri; Ravinder      Punia; Savita      Nagoria; Suchita      Sindhu
Abstract

This review aims to collate literature work reported by researchers (from 1994 to 2021) to provide an overview of the available methodologies for the synthesis and diverse pharmacological activities exhibited by pyrazole based molecules. This review highlights recent reports on various routes of synthesis and potential biological evaluation studies viz. anticancer, AT (II) inhibitory, antiinflammatory activities, HIV-1-RT inhibitory, antihypertensive, herbicidal, antitubercular, insecticidal, antiviral, antimicrobial, and COX-2 inhibitory activity, etc., of pyrazole derivatives and also presents recent efforts made on this heterocyclic moiety.
Keywords: Pyrazole, 1, 3-dicarbonyl compounds, α, β-unsaturated compounds, 3-dipolar cycloaddition, pharmacological activities, anticancer, anti-inflammatory, herbicidal.
Graphical Abstract

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Cite As
Mini-Reviews in Organic Chemistry

A New Insight into the Synthesis and Biological Activities of Pyrazole based Derivatives

Abstract

Graphical Abstract
