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Mini-Reviews in Organic Chemistry

Author(s): Monica Dinodia*

DOI: 10.2174/1570193X19666211231101747

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N-heterocycles: Recent Advances in Biological Applications

Page: [735 - 747] Pages: 13

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Abstract

Nitrogen based heterocycles display an impressive repertoire of biological activities, including antioxidant, antimicrobial, anti-tuberculosis, analgesic, anti-inflammatory, anti-viral, anti-HIV, anticancer, anti-helminthic, and other pharmacological activities. Numerous novel nitrogen-based heterocycles have been synthesized, which showed various physiological properties, and their application in medicinal chemistry is ever-growing. The present review will provide an in-depth view of Nheterocyclic compounds that showed biological activities in the last 5 years (2017-2021). This review article will be helpful for the structural design of effective and sustainable N-heterocyclic drugs against diseases with minimal side effects.

Keywords: Synthesis, drugs, biological activities, nitrogen based heterocycles, biological applications, medicinal chemistry.

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