Abstract

An efficient and eco-friendly approach for the synthesis of β-enaminone derivatives is described by adding nitriles with β-dicarbonyl compounds under ultrasound irradiation conditions at room temperature. The scope and limitation of this strategy are also discussed. A variety of substituted amides can be obtained in moderate to good yields. We hope that this protocol for the efficient synthesis of β-enaminones will offer insights into further investigations.

Keywords: Tin, catalysis, β-dicarbonyl compounds, ultrasound irradiation, enaminone, synthesis.