Abstract
Currently, the world is facing the emergence of a virus that causes pneumonia
in humans, which has a higher probability of causing complications, including respiratory
distress syndrome and death. The new coronavirus 2019 (2019-nCoV), which is currently
known as SARS-CoV-2, is the cause of the Coronavirus disease 2019 (COVID-19). This
virus was first detected in Wuhan, Hubei Province of China, and appears to have been a
zoonotic infection that has now adapted to humans. On March 11, 2020, COVID-19 was
announced as a pandemic by the World Health Organisation (WHO), causing widespread
panic worldwide. SARS-CoV-2 is genetically similar to the 2003 Severe Acute Respiratory
Syndrome-related (SARS) and shares many similarities with the disease features of
influenza virus infection. Scientists around the world are racing towards the development
of vaccines and antivirals for COVID-19. This review will provide an update of COVID-19,
a brief review of the symptoms and route of transmission of the SARS-CoV-2 virus, the
reason why it is highly infectious, as well as the currently available treatments and
comorbidities.
Keywords:
Coronavirus disease 2019, COVID-19, SARS-CoV-2, influenza, pandemic, infection.
[1]
Naming the coronavirus disease (COVID-19) and the virus that causes it. World Health Organization (WHO) 2020. Archived from the original on February 28 2020.
[3]
Coronavirus: What is a pandemic and why use the term now?. BBC News 2020.
[4]
Coronavirus Disease 2019 (COVID-19) Symptoms.Centers for Disease Control and Prevention February 10 2020. Archived from the original on January 30 2020.
[5]
Anosmia Hyposmia. and Dysgeusia Symptoms of Coronavirus Disease American Academy of Otolaryngology-Head and neck surgery March 22 2020 Archived from the original on March 24 2020 Retrieved March 25 2020
[6]
What is a pandemic, and does it change the approach to coronavirus? The guardian.com 2020.
[7]
Q&A on coronaviruses. World Health Organization (WHO) Archived from the original on January 20 2020. Retrieved January 27 2020.
[9]
How does the coronavirus compare with the flu? The New York Times, August 25, 2020.
[10]
Rothan HA, Byrareddy SN. The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak. J Autoimmun 2020; 109: 102433.
[31]
Wrapp D, Wang N, Corbett KS, et al. Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation. Science 2020; 367: 1260-3.
[33]
Coronavirus cases. Worldometer Info.