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Cardiovascular & Hematological Disorders-Drug Targets

Author(s): Prakrati Yadav, Deepak Kumar*, Durga S. Meena, Naresh K, Midha, Gopal K. Bohra, Mahendra K. Garg and Abhishek H.L. Purohit

DOI: 10.2174/1871529X21666210914113752

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Post-Discharge Prophylactic Anticoagulation in COVID-19 Patients: A Clinical Dilemma

Page: [206 - 209] Pages: 4

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Abstract

Background: COVID-19 pandemic has taken a great toll on the health care system worldwide. Along with the pandemic, there is also a concern regarding post COVID-19 complications in recovered patients. Thromboembolism (TE) has been reported as a fatal complication in recovered patients with COVID-19. There is still a great dilemma in post-discharge TE prophylaxis and its long-term benefits.

Case Description: We reported three cases of post COVID-19 with complications related to both diseases as well as post discharge anticoagulant therapy. The first case is about a 60-yr-old male who developed Covid-19 pneumonia (moderate disease) and was discharged on rivaroxaban after initial improvement. 3 weeks later, the patient was readmitted with lower gastro-intestinal bleeding. The other two cases developed pulmonary thromboembolism within a span of 2-3 months (after recovered from COVID-19 pneumonia). Both these patients were not prescribed anticoagulants for TE prophylaxis.

Conclusion: There is an imperative need for effective guidelines for post discharge TE prophylaxis in COVID-19.

Graphical Abstract

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