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Mini-Reviews in Medicinal Chemistry

Author(s): Li Liu, Huiyun Wang, Xiaoyun Chai*, Qingguo Meng*, Sheng Jiang and Fenglan Zhao

DOI: 10.2174/1389557521666210913114631

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Advances in Biocatalytic Synthesis, Pharmacological Activities, Pharmaceutical Preparation and Metabolism of Ginsenoside Rh2

Page: [437 - 448] Pages: 12

  • * (Excluding Mailing and Handling)

Abstract

Ginsenoside Rh2 (3β-O-Glc-protopanaxadiol), a trace but characteristic pharmacological component of red ginseng, exhibited versatile pharmacological activities, such as antitumor effects, improved cardiac function and fibrosis, anti-inflammatory effects, antibiosis and excellent medicinal potential. In recent years, increased research has been performed on the biocatalytic synthesis of ginsenoside Rh2. In this paper, advances in the biocatalytic synthesis, pharmacological activities, pharmaceutical preparation and metabolism of ginsenoside Rh2 are reviewed.

Keywords: Ginsenoside Rh2, biocatalytic synthesis, pharmacological activity, pharmaceutical preparation, metabolism, Panax notoginseng waste.

Graphical Abstract

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