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Current Cardiology Reviews

Author(s): Ikechukwu Ifedili, Kristina Mouksian, David Jones, Ibrahim El Masri, Mark Heckle, John Jefferies and Yehoshua C. Levine*

DOI: 10.2174/1573403X17666210729101752

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Ablation Therapy for Persistent Atrial Fibrillation

Article ID: e290721195115 Pages: 7

  • * (Excluding Mailing and Handling)

Abstract

Atrial Fibrillation (AF) is the most common form of electrical disturbance of the heart and contributes to significant patient morbidity and mortality. With a better understanding of the mechanisms of atrial fibrillation and improvements in mapping and ablation technologies, ablation has become a preferred therapy for patients with symptomatic AF. Pulmonary Vein Isolation (PVI) is the cornerstone for AF ablation therapy, but particularly in patients with AF occurring for longer than 7 days (persistent AF), identifying clinically significant nonpulmonary vein targets and achieving durability of ablation lesions remains an important challenge.

Keywords: Atrial fibrillation, ablation, pulmonary vein isolation, cryoballoon, radiofrequency, left atrium.

Graphical Abstract

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