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Letters in Organic Chemistry

Author(s): Zhongjie Xu, Shaofei Bai, Liyan Shen, Yong Luo* and Zuming Hu*

DOI: 10.2174/1570178618666210610170638

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Synthesis of Stable Isotope Labeled D5-Cyhalothrin, D5-Fenpropathrin and D5-Fenvalerate from Deuterium Phenol

Page: [453 - 456] Pages: 4

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Abstract

A convenient synthetic route of deuterium-labeled D5-cyhalothrin, D5-fenpropathrin, and D5-fenvalerate is described with 98.7%, 98.5%, and 98.3% isotopic enrichment and high chemical purities using D6-phenol as labeled starting material. These structures and isotope-abundance were confirmed by 1H NMR and mass spectrometry. The prepared D5-cyhalothrin, D5-fenpropathrin, and D5- fenvalerate can be used as a standard internal reagent for the determination of residual pyrethroids of food and environment.

Keywords: D5-cyhalothrin, D5-fenpropathrin, D5-fenvalerate, isotopic abundance, food safety, standard internal reagent.

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