Abstract
Background: Flavonoids are a large class of phenolic compounds, which generally refer
to two benzene rings (A ring, B ring) with phenolic hydroxyl groups connected to each other
through three central carbon atoms, that is, a series of C6-C3-C6 basic core compounds. Due to its
potential medicinal value, the research on flavonoids has aroused great interest.
Methods: This review aims to identify the research progress and development trends of electrochemical
analysis of flavonoids. We retrieved published papers (1998-2020) from the Scientific
Citation Index Expanded (SCIE) database of the WoS with a topic search related to the electrochemical
analysis of flavonoids.
Results: In this paper, the research progress in electrochemical analysis of flavonoids has been reviewed.
The antioxidant activity of flavonoids has attracted considerable attention because it directly
affects the application of flavonoids. Different analytical methods also received the attention
of researchers, such as cyclic voltammetry and capillary electrophoresis. This is because the advanced
analysis technology can be useful for evaluating the property of flavonoids.
Conclusion: The research progress and development trends were analyzed based on CiteSpace
software of text mining and visualization. Most research papers on this topic were published in the
years 2004-2005, 2011-2013 and 2016-2018. Different countries are conducting research on the
electrochemical analysis of flavonoids, which are not related to each other.
Keywords:
Electrochemical analysis, flavonoids, sensor, knowledge domain, citespace, herbal medicine.
Graphical Abstract
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