Current Organic Chemistry

Author(s): Ghodsi Mohammadi Ziarani*, Marzieh Rad, Fatemeh Mohajer, Hitesh Sehrawat and Ravi Tomar*

DOI: 10.2174/1385272825666210303112858

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Synthesis of Heterocyclic Compounds through Multicomponent Reactions Using 6-Aminouracil as Starting Reagent

Page: [1070 - 1095] Pages: 26

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Abstract

The analogs of 6-Amino uracil are essential components due to their biological activities. The uracil is used as an important component for the synthesis of heterocyclic compounds like pyrrolo-, pyrido-, pyrimidine-pyrimido scaffolds. Herein, the application of this compound is reviewed as a precursor in the synthesis of many heterocyclic cores from 2016 to 2020.

Keywords: 6-Amino uracil, pyrimidine derivatives, fused spirooxindole, multicomponent reaction, heterocyclic compounds, biological activities.