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Current Bioactive Compounds

Author(s): Ameneh Mohammadi, Parastoo Z. Moghaddam, Seyed A. Hashemi, Peiman Alesheikh and Jamal Kasaian*

DOI: 10.2174/1573407216999201208204839

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Evaluation of Antimicrobial and Antioxidant Activities of Latex and Extracts of Euphorbia monostyla

Article ID: e010621188866 Pages: 5

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Abstract

Objective: Euphorbia is a plant from the Euphorbiaceae family, and it has traditionally been used to treat gonorrheal, respiratory tract infections, skin infections and malaria. The aim of the present study was to evaluate antibacterial, antifungal and antioxidant activities of latex and extracts of Euphorbia monostyla.

Materials and Methods: Antimicrobial activity was studied by Disc-well diffusion and MIC-MBC methods.Also, its antioxidant activity was evaluated by DPPH and FRAP methods. Total phenolic content was evaluated by Folin-Ciocalteu reagent.

Results: It is displayed as a result of the work that solvent polarity will play a key role in increasing phenolic solubility. Methanol extract gave the highest percentage yield, and ethyl acetate resulted in the lowest percentage yield. The antimicrobial test showed that whole extracts had no beneficial uses on microorganisms in comparison to antibiotics types. Analysis of antioxidant assays revealed that aqueous and methanol extracts had the highest antioxidant properties.

Conclusion: Whole extracts had no beneficial uses on microorganisms compared to antibiotics types, but the aqueous extract of E. monostyla had moderate antioxidant activity and may contain valuable active compounds. This work is the first study that discusses E. monostyla, and further study is suggested to isolate its active compounds.

Keywords: Euphorbia monostyla, antibacterial, antifungal, antioxidant, asthma, sterols.

Graphical Abstract

[1]
Kaur N, Bhatia A, Sidhu S. Evaluation of atibacterial activity of plant extracts of euphorbia thymifolia against human pathogenic bacteria. Int J Emer Res Manag & Tech 2017; 6(8): 335-8.
[2]
Nasseh Y, Nazarova E, Kazempour S. Taxonomic revision and phytogeographic studies in Euphorbia (Euphorbiaceae) in the Khorassan provinces of Iran. Nord J Bot 2018; 36(5)
[http://dx.doi.org/10.1111/njb.01413]
[3]
Sultan S, Kimaro C, Amri E. Antifungal Activity and Phytochemical Screening of Different Solvent Extracts of Euphorbia tirucalli Linn J adv biol biotechnol 2016; 7(1): 1-9.
[4]
Vimal JB, Das SSM. Antifungal activity of Euphorbia antiquorum L. latex an in vitro study. Int J Appl Eng Res 2015; 1(3): 25-8.
[5]
Mazandarani M, ZARGHAMI MP, BAYAT H, Zolfaghari MR, GHAEMI E, Hemati H. Antioxidant activity, phenol, flavonoid and anthocyanin contents in various extracts of Onosma dichroanthum Boiss. in north of Iran. Iran. J Plant Physiol 2011; 1(3): 169-76.
[6]
Abubakar E. Antibacterial activity of crude extracts of Euphorbia hirta against some bacteria associated with enteric infections. J Med Plants Res 2009; 3(7): 498-505.
[7]
Caetano ACS, Araújo CRd, Lima VLAGd, Maciel MIS, Melo EA. Evaluation of antioxidant activity of agro-industrial waste of acerola (Malpighia emarginata DC) fruit extracts. Food Sci Technol 2011; 31(3): 769-75.
[http://dx.doi.org/10.1590/S0101-20612011000300034]
[8]
Pérez-Jiménez J, Arranz S, Tabernero M, et al. Updated methodology to determine antioxidant capacity in plant foods, oils and beverages: Extraction, measurement and expression of results. Food Res Int 2008; 41(3): 274-85.
[http://dx.doi.org/10.1016/j.foodres.2007.12.004]
[9]
Kamali M, Khosroyar S, Mohammadi A. Antibacterial activity of various extracts from Dracocephalum kotschyi against food pathogenic microorganisms. Int J Pharm Tech Res 2015; 8(9): 158-63.
[10]
Moghaddam PZ, Mohammadi A, Feyzi P, Alesheikh P. In vitro antioxidant and antibacterial activity of various extracts from exocarps and endocarps of walnut. Pak J Pharm Sci 2017; 30(5): 1725-31.
[PMID: 29084695]
[11]
Kang W, Yang H, Hong HJ, Han CH, Lee YJ. Anti-oxidant activities of kiwi fruit extract on carbon tetrachloride-induced liver injury in mice. Korean J Vet Res 2012; 52(4): 270-80.
[12]
Tenkerian C, El-Sibai M, Daher CF, Mroueh M. Hepatoprotective, antioxidant, and anticancer effects of the tragopogon porrifolius methanolic extract. Evid Based Complement Alternat Med 2015; 2015
[http://dx.doi.org/10.1155/2015/161720] [PMID: 25694787]
[13]
Ku KM, Juvik JA. Environmental stress and methyl jasmonate- mediated changes in flavonoid concentrations and antioxidant activity in broccoli florets and kale leaf tissues. HortScience 2013; 48(8): 996-1002.
[http://dx.doi.org/10.21273/HORTSCI.48.8.996]
[14]
Namvar K, Mohammadi A, Ataei Salehi E, Feyzi P. Evaluation of solvent effect (methanol: Water mixture) on the phenolic content and antioxidant activities of Stachys turcomanica Trautv. Pharm Sci 2017; 23(3): 248-4.
[http://dx.doi.org/10.15171/PS.2017.36]
[15]
Khan AM, Qureshi RA, Gillani SA, Ullah F. Antimicrobial activity of selected medicinal plants of Margalla Hills, Islamabad, Pakistan. J Med Plants Res 2011; 5(18): 4665-70.
[16]
Gayathri A, Ramesh KV. Antifungal activity of Euphorbia hirta L. inflorescence extract against Aspergillus flavus-A mode of action study. Int J Curr Microbiol Appl Sci 2013; 4: 31-7.
[17]
Ughachukwu P, Ezenyeaku C, Ochiogu B, Ezeagwuna D, Anahalu I. Evaluation of antibacterial activities of Euphorbia heterophylla. IOSR J Dent Med Sci 2014; 13: 69-75.
[http://dx.doi.org/10.9790/0853-131146975]
[18]
Velioglu Y, Mazza G, Gao L, Oomah B. Antioxidant activity and total phenolics in selected fruits, vegetables, and grain products. J Agric Food Chem 1998; 46(10): 4113-7.
[http://dx.doi.org/10.1021/jf9801973]
[19]
de Araújo KM, de Lima A, Silva JdoN, et al. Identification of phenolic compounds and evaluation of antioxidant and antimicrobial properties of Euphorbia tirucalli L. Antioxidants 2014; 3(1): 159-75.
[http://dx.doi.org/10.3390/antiox3010159] [PMID: 26784670]
[20]
Munro B, Vuong QV, Chalmers AC, Goldsmith CD, Bowyer MC, Scarlett CJ. Phytochemical, antioxidant and anti-cancer properties of Euphorbia tirucalli methanolic and aqueous extracts. Antioxidants 2015; 4(4): 647-61.
[http://dx.doi.org/10.3390/antiox4040647] [PMID: 26783950]
[21]
Venumadhav K, Seshagirirao K. Phytochemical screening and Antioxidant activity of Euphorbia caducifolia extracts. Int J Pharm Sci Res 2017; 8: 92-6.
[22]
Kowalczyk D, Biendl M. Physicochemical and antioxidant properties of biopolymer/candelilla wax emulsion films containing hop extract–A comparative study. Food Hydrocoll 2016; 60: 384-92.
[http://dx.doi.org/10.1016/j.foodhyd.2016.04.010]
[23]
Farhan H, Rammal H, Hijazi A, et al. Chemical composition and antioxidant activity of a Lebanese plant Euphorbia macroclada schyzoceras. Asian Pac J Trop Biomed 2013; 3(7): 542-8.
[http://dx.doi.org/10.1016/S2221-1691(13)60110-0] [PMID: 23836193]
[24]
Kwon YR, Lee HR, Hwang SH, Kwon OJ, Youn KS. Antioxidant activities and physiological properties of Euphorbia humifusa extracts prepared using different solvents. Korean J Food Preserv 2016; 23(2): 252-8.
[http://dx.doi.org/10.11002/kjfp.2016.23.2.252]