Abstract

The benzo[b]thiophene nucleus is ubiquitous in biologically and pharmaceutically important compounds. These moieties are highly important in materials science. The synthesis of benzothiophene as a privileged structure has readily become a subject of great interest and actively pursued in recent years. This review focuses on facile and convenient methods of synthesis of benzo[b]thiophene based molecules through different transition metals catalyzed reactions.

Keywords: Benzo[b]thiophene, couplings, transition metals, heterocyclics, palladium, synthesis.