A Comprehensive Study of Pharmacological Behaviors, Nano-Formulations, and Applications of Rosemary

Page: [629 - 647] Pages: 19

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Abstract

Aim: The purpose of this review paper is to elaborate many nano-formulations of Rosemary which are used against many diseases and also explain the Pharmacological activity of phytocompounds of Rosemary and detail about the applications and uses of Rosemary in many fields.

Objectives: Rosemary (Rosmarinus officinalis L.) is a medicinal herbal plant; their leaves are used in Europe, America, and Asia as a food additive. It is very valuable; its parts contain many chemical constituents which are very effective against many diseases like diabetes, obesity, cancer, infections and also have antioxidant, anti-inflammation, memory-improvement, etc. properties.

Results: In the literature reviewed, Rosmarinus officinalis (rosemary) has shown exciting potential both as a natural food preservative and therapeutic agent. Rosemary (Rosmarinus officinalis) essential oil has been extensively studied due to its chemical composition and biological activities. The extract of Rosemary also shows medicinal properties like anticancer, antimicrobial, antidiabetic, anti- inflammatory, etc. From many studies, it was also found that nano-formulation of Rosemary had been developed by using the Rosemary essential oil and its extract used in the diagnosis and treatment of many diseases.

Conclusion: From the conventional times, therapeutic effects of Rosemary are seen, which is also used in Modern Medicine nowadays. It had been used as food additives in conventional times. In renal colic and dysmenorrhea, it is used as an antispasmodic to relieve respiratory disorders and to boost hair development. CNS, cardiac and locomotive activity promote inhalation and oral administration of Rosemary oil, suggesting the direct effect of one or more of its constituents. Rosemary has curative potential in the therapy and avoidance of bronchial asthma, peptic ulcer, spasmodic disorders, inflammatory illnesses, atherosclerosis, hepatotoxicity, cancer, ischemic heart illness, bad sperm motility, Alzheimer, and may act as an antidepressant and anxiolytic properties.

Keywords: Rosemary, rosmarinic acid, carnosol, pharmacological actions, extraction, nano-formulations.

Graphical Abstract