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Coronaviruses

Author(s): S.V. Ramesh*, R. Pandiselvam, K.B. Hebbar, M.R. Manikantan, P.P. Shameena Beegum, Shelly Praveen and N.U. Sruthi

DOI: 10.2174/2666796701999201104164010

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Antiviral Potential of Coconut (Cocos nucifera L.) Oil and COVID-19

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Abstract

Background: COVID-19 caused by the novel SARS Coronavirus-2 (SARS-CoV-2) is causing serious problems in the global public health sphere. In the absence of a powerful antiviral treatment, the exploration of plant-based products with antiviral potential has gained interest.

Scope and Approach: This commentary presents the prospects of utilizing coconut oil directly or its derivatives such as monolaurin in treating COVID-19 with a special emphasis on their biochemical characteristics features. The potential pitfalls therein and way forward are also highlighted.

Key findings and conclusions: There are enough research-backed evidences to demonstrate the antiviral capabilities of coconut oil and monolaurin. The possibility of developing a medium-chain fatty acidbased nasal spray as a prophylactic or therapeutic is also discussed. Nevertheless, the potential impediments in devising suitable therapeutic models to treat SARS-CoV-2, are presented.

Keywords: Antiviral therapy, immune-modulation, medium-chain fatty acids, lauric acid, SARS-CoV-2, Cocos nucifera L.

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