Background: Severe Acute Respiratory Syndrome Coronavirus 2 has affected millions of people, and especially in adult patients with underlying diseases lead to death. Meanwhile pediatric patients with inherited defects of T cell should be prone to viral diseases.
Case Presentation: Herein, we report an infant with severe combined immunodeficiencies, who were affected and died because of COVID-19.
Conclusion: Considering the importance of finding how immune system can affect the viral infection, presentation of COVID-19 in immune deficient patients can be valuable.
Keywords: Combined immunodeficiency, COVID-19, cardiac injury, infant, death, bone marroow.