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Current Genomics

Author(s): Yirui Cao, Yue Qiu, Guowei Tu* and Cheng Yang*

DOI: 10.2174/1389202921999201020203249

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Single-cell RNA Sequencing in Immunology

Page: [564 - 575] Pages: 12

  • * (Excluding Mailing and Handling)

Abstract

The complex immune system is involved in multiple pathological processes. Single-cell RNA sequencing (scRNA-seq) is able to analyze complex cell mixtures correct to a single cell and single molecule, thus is qualified to analyze immune reactions in several diseases. In recent years, scRNA-seq has been applied in many researching fields and has presented many innovative results. In this review, we intend to provide an overview of single-cell RNA sequencing applications in immunology and a prospect of future directions.

Keywords: Single-cell RNA sequencing, immunology, cancer, autoimmune disease, transplantation, tumors.

Graphical Abstract

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