Abstract

Infertility is defined as the inability to conceive a pregnancy after one year or more of unprotected sexual intercourse, among the women at the risk of conceiving a pregnancy. In addition to the age factor, it is known to be associated with pathological and genetic conditions that contribute to its early onset. Polycystic ovarian syndrome (PCOS), endometriosis, fibroids, and blockade in fallopian tubes are certain common pathological causes of female infertility. Researches are focused to eradicate the primary cause of infertility to achieve healthy fertile ground for fertilization. Depending on the cause, therapeutic options include medicines (chemical, herbal and Chinese), hormonal stimulation, surgery, assistive reproductive technology, and tissue engineering. To the extent of research, biotechnology has played a significant role to answer the problem. This review discusses advancements in these therapeutic fields to treat women-associated infertility.

Keywords: Polycystic ovarian syndrome (PCOS), infertility, fertilization, women, tissue engineering, hormonal stimulation.

Graphical Abstract