Current Topics in Medicinal Chemistry

Author(s): He Huang, Chuanjun Song* and Junbiao Chang

DOI: 10.2174/1568026620666200922115109

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Synthesis and Biological Activity Study of Tanshinone Derivatives: A Literature and Patent Review

Page: [2520 - 2534] Pages: 15

  • * (Excluding Mailing and Handling)

Abstract

Tanshinones are a class of bioactive compounds present in the Chinese herbal medicine Danshen (Salvia miltiorrhiza Bunge), containing among others, abietane diterpene quinone scaffolds. Chemical synthesis and biological activity studies of natural and unnatural tanshinone derivatives have been reviewed in this article.

Keywords: Danshen, Tanshinone, Chemical synthesis, Structural modification, Biological activity, Herbal medicine.