Abstract
Musculoskeletal tumors of the hand are a rare entity and are divided into skeletal and
soft tissue tumors. Either category comprises benign and malignant or even intermediate tumors.
Basic radiology allows an optimal resolution of bone and related soft tissue areas, ultrasound and
more sophisticated radiologic tools such as scintigraphy, CT and MRI allow a more accurate evaluation
of tumor extent. Enchondroma is the most common benign tumor affecting bone, whereas
chondrosarcoma is the most commonly represented malignant neoplasm localized to hand bones.
In the soft tissues, ganglions are the most common benign tumors and epithelioid sarcoma is the
most frequently represented malignant tumor targeting hand soft tissues. The knowledge regarding
diagnostic and therapeutic management of these tumors is often deriving from small case series, retrospective
studies or even case reports. Evidences from prospective studies or controlled trials are
limited and for this lack of clear and supported evidences, data from the medical literature on the
topic are controversial, in terms of demographics, clinical presentation, diagnosis, prognosis and
therapy. The correct recognition of the specific subtype and extension of the tumor through first
line and second line radiology is essential for the surgeon, in order to effectively direct the therapeutic
decisions.
Keywords:
Hand tumors, hand oncology, hand primary tumors, musculoskeletal tumors, enchondroma, MRI.
Graphical Abstract
[23]
Xie C, Tsakok M, Taylor N, et al. Imaging of brown tumours: a pictorial review Insights Imaging 2019; 10(1): 75-387.
[24]
Nakamura K, Nanjyo B. An unusual periosteal osteochondromatous proliferation in the hand Plast Reconstr Surg 1994; 94: 384-7.
[34]
Huvos AG. Bone Tumors: Diagnosis, Treatment and Prognosis. 2nd ed. Philadelphia: WB Saunders 1991.
[44]
Schwartz HS, Zimmerman NB, Simon MA, et al. The malignant potential of enchondromatosis J Bone Joint Surg Am 1987; 69: 269-74.
[69]
Puhaindran ME, Athanasian EA. Malignant and metastatic tumors of the hand J Hand Surg 2010; 35: 1895.
[70]
Dahlin DC, Salvador AH Chondrosarcomas of bones of the hands and feet-a study of 30 cases Cancer 1974; 34: 755-60.
[97]
Coley BL, Higinbotham NL. Tumors primary in the bones of the hands and feet. Surgery 1939; 5: 112-28.
[150]
Stoller DW, Tirman PF, Bredella MA, Beltran S. Diagnostic Imaging: Orthopaedics. Salt Lake City: Amirsys 2004; Vol. 8.
[152]
Sultan I, Rodriguez-Galindo C, Saab R, et al. Comparing children and adults with synovial sarcoma in the surveillance, epidemiology, and end results program, 1983 to 2005: An analysis of 1268 patients Cancer 2009; 115: 3537.
[153]
Corey RM, Swett K, Ward WG. Epidemiology and survivorship of soft tissue sarcomas in adults: A national cancer database report. Cancer Med 2014; 3: 1404-15.
[163]
Demas BE, Heelan RT, Lane J, et al. Sof tissue sarcomas of the extremitities: Comparison of MR and CT in determining the extent of disease. ATR Am J Roentgenol 1988; 150: 615-20.
[164]
Hadju SI. Differential diagnosis of soft tissue and bone tumors. Philadelphia: Lea & Febiger 1986.
[176]
Athanasian EA. Bone and soft tissue tumors. 2011. Annual Meeting Abstract.